Xin Yan-Hua, Guo Ying-Qiong, Zhang Xing-Guo, Deng Chen-Liang
College of Chemistry and Materials Engineering, Wenzhou University, Wenzhou 325035, China.
Guangxi Key Laboratory of Calcium Carbonate Resources Comprehensive Utilization, Hezhou University, Hezhou 542899, China.
J Org Chem. 2021 Dec 3;86(23):17496-17503. doi: 10.1021/acs.joc.1c02188. Epub 2021 Nov 8.
A novel and efficient method for the synthesis of methyl sulfone derivatives via palladium-catalyzed methylsulfonylation of alkyl halides with dimethyl sulfite has been described. A variety of aryl and alkyl iodides underwent the sulfonylation smoothly to furnish methyl sulfites in moderate to excellent yields.
描述了一种通过钯催化卤代烃与亚硫酸二甲酯的甲基磺酰化反应合成甲基砜衍生物的新颖且高效的方法。多种芳基和烷基碘化物顺利进行磺酰化反应，以中等至优异的产率得到亚硫酸甲酯。
