Wedenberg C, Lindskog S
Scand J Dent Res. 1987 Jun;95(3):205-11. doi: 10.1111/j.1600-0722.1987.tb01832.x.
The ability of stimulated and unstimulated peritoneal macrophages to spread in vitro on different inorganic and organic components of dental tissues was studied in order to establish morphologic evidence in favor of a resorption inhibitor in dentin. Macrophages were seeded onto enamel, dentin, predentin, demineralized dentin and collagen-coated coverslips and examined with scanning electron microscopy after varying incubation periods. The cells readily attached and spread on enamel, dentin and collagen-coated coverslips. Cells attached but showed no signs of spreading when incubated on predentin or demineralized dentin. It was concluded that the resistance to resorption of predentin and dentin rests in the organic, non-collagenous component of the tissue, indicating the presence of a resorption inhibitor in dentin.
为了找到支持牙本质中存在吸收抑制剂的形态学证据，研究了刺激和未刺激的腹膜巨噬细胞在体外于牙齿组织的不同无机和有机成分上扩散的能力。将巨噬细胞接种到釉质、牙本质、前期牙本质、脱矿牙本质和胶原包被的盖玻片上，在不同孵育时间后用扫描电子显微镜检查。细胞很容易附着并在釉质、牙本质和胶原包被的盖玻片上扩散。当在前期牙本质或脱矿牙本质上孵育时，细胞附着但没有扩散的迹象。得出的结论是，前期牙本质和牙本质对吸收的抵抗力在于组织的有机、非胶原成分，这表明牙本质中存在吸收抑制剂。
