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Combustible and Electronic Cigarette Exposures Increase ACE2 Activity and SARS-CoV-2 Spike Binding.

作者信息

Ghosh Arunava, Girish Vishruth, Yuan Monet Lou, Coakley Raymond D, Wrennall Joe A, Alexis Neil E, Sausville Erin L, Vasudevan Anand, Chait Alexander R, Sheltzer Jason M, Tarran Robert

机构信息

University of North Carolina at Chapel Hill Chapel Hill, North Carolina.

Cold Spring Harbor Laboratory Cold Spring Harbor New York.

出版信息

Am J Respir Crit Care Med. 2022 Jan 1;205(1):129-133. doi: 10.1164/rccm.202106-1377LE.

DOI:10.1164/rccm.202106-1377LE
PMID:34748720
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8865588/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3717/8865588/b7fa355e23f8/rccm.202106-1377LEf2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3717/8865588/ba403a6b00c7/rccm.202106-1377LEf1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3717/8865588/b7fa355e23f8/rccm.202106-1377LEf2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3717/8865588/ba403a6b00c7/rccm.202106-1377LEf1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3717/8865588/b7fa355e23f8/rccm.202106-1377LEf2.jpg

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本文引用的文献

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Chronic E-Cigarette Aerosol Inhalation Alters the Immune State of the Lungs and Increases ACE2 Expression, Raising Concern for Altered Response and Susceptibility to SARS-CoV-2.长期吸入电子烟烟雾会改变肺部的免疫状态并增加血管紧张素转换酶2(ACE2)的表达,引发对SARS-CoV-2反应改变和易感性增加的担忧。
Front Physiol. 2021 May 31;12:649604. doi: 10.3389/fphys.2021.649604. eCollection 2021.
2
Sex differences in the induction of angiotensin converting enzyme 2 (ACE-2) in mouse lungs after e-cigarette vapor exposure and its relevance to COVID-19.电子烟蒸气暴露后小鼠肺部血管紧张素转换酶 2(ACE-2)诱导的性别差异及其与 COVID-19 的相关性。
J Investig Med. 2021 Jun;69(5):954-961. doi: 10.1136/jim-2020-001768. Epub 2021 Apr 29.
3
深入了解大众电子烟气溶胶及其成分如何影响 SARS-CoV-2 感染人体支气管上皮细胞。
Sci Rep. 2023 Apr 10;13(1):5807. doi: 10.1038/s41598-023-31592-x.
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Synergistic Detrimental Effects of Cigarette Smoke, Alcohol, and SARS-CoV-2 in COPD Bronchial Epithelial Cells.香烟烟雾、酒精和SARS-CoV-2对慢性阻塞性肺疾病支气管上皮细胞的协同有害影响。
Pathogens. 2023 Mar 22;12(3):498. doi: 10.3390/pathogens12030498.
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Activities Carried Out during the First COVID-19 Lockdown by Italian Citizens.意大利公民在第一次 COVID-19 封锁期间开展的活动。
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