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Divergent humoral responses in mild to moderate SARS-CoV-2 infection over time - indication of persistence of the virus?

作者信息

Bürgi Justus J, Rösslein Matthias, Hornung Henry, Jentsch Jana, Boller Viveka L, Dollenmaier Günter, Wick Peter, Peier Karen, Nohynek Brigitte, Fischer Aldo, Stolz Raphael, Cettuzzi Michele, Reut Michael, Boy Regine Garcia, Nolte Oliver, Korte Wolfgang

机构信息

Center for Laboratory Medicine, Frohbergstrasse 3, 9000 St. Gallen, Switzerland.

Empa - Swiss Federal Laboratories for Materials Science and Technology, Lerchenfeldstrasse 5, 9014 St. Gallen, Switzerland; Cantonal Corona Study Group, Oberer Graben 32, 9001 St. Gallen, Switzerland.

出版信息

J Infect. 2022 Mar;84(3):418-467. doi: 10.1016/j.jinf.2021.11.001. Epub 2021 Nov 6.

DOI:10.1016/j.jinf.2021.11.001
PMID:34748825
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8570801/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b35b/8570801/7142c0089b47/gr2_lrg.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b35b/8570801/ab7b9ccfa42b/ga1_lrg.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b35b/8570801/fa13e6fed742/gr1_lrg.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b35b/8570801/7142c0089b47/gr2_lrg.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b35b/8570801/ab7b9ccfa42b/ga1_lrg.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b35b/8570801/fa13e6fed742/gr1_lrg.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b35b/8570801/7142c0089b47/gr2_lrg.jpg

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Nat Commun. 2021 May 11;12(1):2670. doi: 10.1038/s41467-021-22958-8.
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SARS-CoV-2 Reinfection in a Healthcare Worker Despite the Presence of Detectable Neutralizing Antibodies.SARS-CoV-2 再感染，尽管存在可检测的中和抗体。
Viruses. 2021 Apr 12;13(4):661. doi: 10.3390/v13040661.
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Protection against SARS-CoV-2 infection by a mucosal vaccine in rhesus macaques.
黏膜疫苗对恒河猴感染 SARS-CoV-2 的保护作用。
JCI Insight. 2021 Apr 28;6(10):148494. doi: 10.1172/jci.insight.148494.
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Time series analysis and mechanistic modelling of heterogeneity and sero-reversion in antibody responses to mild SARS‑CoV-2 infection.轻度SARS-CoV-2感染抗体反应中异质性和血清逆转的时间序列分析及机制建模
EBioMedicine. 2021 Mar;65:103259. doi: 10.1016/j.ebiom.2021.103259. Epub 2021 Mar 2.
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Nature. 2021 Mar;591(7851):639-644. doi: 10.1038/s41586-021-03207-w. Epub 2021 Jan 18.
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