Nosewicz Jacob, Spaccarelli Natalie, Roberts Kristen M, Hart Phil A, Kaffenberger Jessica A, Trinidad John C, Kaffenberger Benjamin H
Division of Dermatology, The Ohio State University Wexner Medical Center, Columbus, Ohio.
Division of Gastroenterology, Hepatology and Nutrition, The Ohio State University Wexner Medical Center, Columbus, Ohio.
J Am Acad Dermatol. 2022 Feb;86(2):267-278. doi: 10.1016/j.jaad.2021.07.079. Epub 2021 Nov 6.
Dermatologists play a critical role in diagnosing and managing nutritional deficiencies as they often present with cutaneous findings. Traditionally, nutritional dermatoses are taught in the context of developing countries, famine, population displacement, and poor health care access; however, in the United States, common risk factors include chronic liver disease, alcoholism, psychiatric disease, bariatric surgery, inflammatory bowel disease, and hemodialysis. Additionally, nutritional dermatoses may be underdiagnosed in the United States and result in increased morbidity and utilization of hospital resources. There is a need for providers in developed nations to identify these deficiencies, and this review aims to meet that practice gap and provide relevant context to these diseases for dermatologists. This 2-part review series will focus on the epidemiology, impact, appearance, and diagnostic modalities for micronutrient deficiencies, including zinc, selenium, copper, and vitamins A and C in part 1. The companion review will focus on the B-complex vitamins.
皮肤科医生在诊断和处理营养缺乏症方面发挥着关键作用，因为营养缺乏症常常会出现皮肤表现。传统上，营养性皮肤病是在发展中国家、饥荒、人口流离失所以及医疗保健可及性差的背景下讲授的；然而，在美国，常见的风险因素包括慢性肝病、酗酒、精神疾病、减肥手术、炎症性肠病和血液透析。此外，营养性皮肤病在美国可能未得到充分诊断，从而导致发病率增加和医院资源利用增加。发达国家的医疗服务提供者有必要识别这些缺乏症，本综述旨在填补这一实践空白，并为皮肤科医生提供这些疾病的相关背景知识。这个分为两部分的综述系列将在第1部分重点关注微量营养素缺乏症的流行病学、影响、表现和诊断方法，包括锌、硒、铜以及维生素A和C。配套综述将重点关注B族维生素。
