Lee Junhyeong, Kim Ui-Jin, Lee Yongho, Han Eunseun, Ham Seunghon, Lee Wanhyung, Choi Won-Jun, Kang Seong-Kyu
Department of Occupational and Environmental Medicine, Gil Medical Center, Incheon, Korea.
Graduate School, Gachon University, Incheon, Korea.
Ann Occup Environ Med. 2021 Jul 16;33:e24. doi: 10.35371/aoem.2021.33.e24. eCollection 2021.
Sunlight exposure is a major risk factor for eye disorders. Most outdoor workers cannot avoid sunlight exposure. This study aimed to analyze the relationship between outdoor sunlight exposure and eye disorders in an economically active population.
This study analyzed the 2008-2012 Korea National Health and Nutritional Examination Survey data. Sunlight exposure was categorized as < 5 hours and > 5 hours. We also analyzed the dose-dependent relationship between exposure to sunlight and eye disorders (cataracts, pterygium, and age-related macular degeneration [AMD]) using data from 2010 to 2012 by subdividing the exposure groups into < 2 hours, 2-5 hours, and ≥ 5 hours. Eye disorders were diagnosed by an ophthalmologist. The study participants were stratified by sex, and the results were analyzed using the χ test and multiple logistic regression analysis.
In the female group, the odds ratio of pterygium in the high-level sunlight exposure group was 1.47 (95% confidence interval [CI]: 1.15-1.89). Regarding AMD, the odds ratios were 1.42 (95% CI: 1.16-1.73), 1.33 (95% CI: 1.03-1.73), and 1.58 (95% CI: 1.15-2.16) in the total, male, and female groups, respectively. Analysis of the dose-response relationship revealed that the odds ratios of pterygium in the high-level sunlight exposure subgroups of the total and female groups were 1.62 (95% CI: 1.25-2.08) and 2.00 (95% CI: 1.39-2.88), respectively.
This study demonstrated a relationship between sunlight exposure and eye disorders in an economically active population. Women were found to be especially vulnerable to pterygium. However, additional prospective studies to clarify the pathophysiology of pterygium are needed.
阳光照射是眼部疾病的主要危险因素。大多数户外工作者无法避免阳光照射。本研究旨在分析经济活跃人群中户外阳光照射与眼部疾病之间的关系。
本研究分析了2008 - 2012年韩国国家健康与营养检查调查数据。阳光照射分为<5小时和>5小时。我们还通过将暴露组细分为<2小时、2 - 5小时和≥5小时,利用2010年至2012年的数据分析了阳光照射与眼部疾病(白内障、翼状胬肉和年龄相关性黄斑变性[AMD])之间的剂量反应关系。眼部疾病由眼科医生诊断。研究参与者按性别分层,结果采用χ检验和多元逻辑回归分析。
在女性组中,高阳光照射组翼状胬肉的优势比为1.47(95%置信区间[CI]:1.15 - 1.89)。关于AMD,总体、男性和女性组的优势比分别为1.42(95%CI:1.16 - 1.73)、1.33(95%CI:1.03 - 1.73)和1.58(95%CI:1.15 - 2.16)。剂量反应关系分析显示,总体和女性组高阳光照射亚组中翼状胬肉的优势比分别为1.62(95%CI:1.25 - 2.08)和2.00(95%CI:1.39 - 2.88)。
本研究证明了经济活跃人群中阳光照射与眼部疾病之间的关系。发现女性尤其易患翼状胬肉。然而,需要进一步的前瞻性研究来阐明翼状胬肉的病理生理学。