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获得性免疫缺陷综合征患者的口腔表现

Oral findings in patients with acquired immunodeficiency syndrome.

作者信息

Phelan J A, Saltzman B R, Friedland G H, Klein R S

出版信息

Oral Surg Oral Med Oral Pathol. 1987 Jul;64(1):50-6. doi: 10.1016/0030-4220(87)90116-2.

DOI:10.1016/0030-4220(87)90116-2
PMID:3475658
Abstract

Oral examinations of 103 consecutive patients with acquired immunodeficiency syndrome (AIDS) were performed. Of these patients, 74 (72%) were heterosexuals and 29 (28%) were homosexual or bisexual men. Lesions that were identified on subsequent examination were recorded separately. Oral candidiasis was the most common finding, occurring in 94 patients. Other findings were herpes simplex ulceration (ten patients), exfoliative cheilitis (nine patients), xerostomia (ten patients), "hairy" leukoplakia (seven patients), and Kaposi's sarcoma (four patients). A patchy, depapillated tongue was seen in six patients, and ulcers with uncertain cause were seen in three patients. Gingival bleeding, perioral molluscum contagiosum, and brown hairy tongue each occurred in one patient. In this study, "hairy" leukoplakia and Kaposi's sarcoma occurred exclusively in homosexual and bisexual men with AIDS, and occurred significantly more frequently in this group than in heterosexual patients with AIDS. There was no significant difference between these groups in the frequency of occurrence of other findings.

摘要

对103例连续的获得性免疫缺陷综合征(AIDS)患者进行了口腔检查。在这些患者中,74例(72%)为异性恋者,29例(28%)为同性恋或双性恋男性。后续检查中发现的病变分别记录。口腔念珠菌病是最常见的发现,94例患者出现。其他发现包括单纯疱疹溃疡(10例患者)、剥脱性唇炎(9例患者)、口干症(10例患者)、“毛状”白斑(7例患者)和卡波西肉瘤(4例患者)。6例患者出现斑片状、乳头消失的舌,3例患者出现病因不明的溃疡。牙龈出血、口周传染性软疣和黑毛舌各有1例患者出现。在本研究中,“毛状”白斑和卡波西肉瘤仅发生在患有AIDS的同性恋和双性恋男性中,且该组的发生率明显高于患有AIDS的异性恋患者。这些组在其他发现的发生率上没有显著差异。

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