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热灭菌会显著降低大多数FFP2和KN-95口罩的过滤效率。

Heat sterilisation dramatically reduces filter efficiency of the majority of FFP2 and KN-95 respirators.

作者信息

van der Vossen Jos M B M, Heerikhuisen Margreet, Traversari Roberto A A L, van Wuijckhuijse Arjan L, Montijn Roy C

机构信息

The Netherlands Organisation for Applied Scientific Research TNO, department of Microbiology and Systems Biology, Utrechtseweg 48, 3704 HE Zeist, the Netherlands.

The Netherlands Organisation for Applied Scientific Research TNO, department of Microbiology and Systems Biology, Utrechtseweg 48, 3704 HE Zeist, the Netherlands.

出版信息

J Hosp Infect. 2020 Oct 22;107:87-90. doi: 10.1016/j.jhin.2020.10.012.

DOI:10.1016/j.jhin.2020.10.012
PMID:34756844
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7581325/
Abstract

BACKGROUND

Because of the enormous demand for personal protective equipment and especially respiratory protective devices (respirators) during the initial phase of the corona pandemic shortages arose. Sterilisation of used respirators can reduce these shortages. In our study, respirator testing was carried out after only one sterilisation cycle.

AIM

To determine if steam sterilisation and reuse could be safely applied for used respirators.

METHODS

In a cabinet an aqueous solution of NaCl (0.02% w/v) was nebulized and passed through a sample of the material of a respirator. Passing particle concentrations were measured directly from the cabinet and via the filter material of the respirator for particles ≥ 0.3 μm, ≥ 0.5 μm and ≥ 1.0 μm.

FINDINGS

only three out of ten steam sterilised respirators met the requirements of 94% filtration efficiency.

CONCLUSION

The results prove that heat sterilisation cannot be generically applied for reuse of respirators safely.

摘要

背景

在新冠疫情初期,由于对个人防护装备尤其是呼吸防护设备(呼吸器)的巨大需求,出现了短缺情况。对用过的呼吸器进行消毒可以减少这些短缺。在我们的研究中,仅在一个消毒周期后就对呼吸器进行了测试。

目的

确定蒸汽消毒和重复使用是否可以安全地应用于用过的呼吸器。

方法

在一个柜子里,将NaCl(0.02% w/v)的水溶液雾化,并使其通过一个呼吸器材料样本。直接从柜子中以及通过呼吸器的过滤材料测量≥0.3μm、≥0.5μm和≥1.0μm颗粒的通过颗粒浓度。

结果

十个蒸汽消毒的呼吸器中只有三个符合94%过滤效率的要求。

结论

结果证明,热消毒不能一概而论地安全应用于呼吸器的重复使用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9c46/7581325/d22127afe44a/gr2_lrg.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9c46/7581325/3db6f33cf491/gr1_lrg.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9c46/7581325/d22127afe44a/gr2_lrg.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9c46/7581325/3db6f33cf491/gr1_lrg.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9c46/7581325/d22127afe44a/gr2_lrg.jpg

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J Hosp Infect. 2020 May 20;105(3):447-53. doi: 10.1016/j.jhin.2020.05.023.
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Disposable masks: Disinfection and sterilization for reuse, and non-certified manufacturing, in the face of shortages during the COVID-19 pandemic.一次性口罩:在新冠疫情期间面临短缺的情况下,进行消毒和灭菌以重复使用,以及未经认证的生产。
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Facemask shortage and the novel coronavirus disease (COVID-19) outbreak: Reflections on public health measures.
Recent developments in filtration media and respirator technology in response to COVID-19.
应对新冠疫情的过滤介质和呼吸器技术的最新进展。
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Filtering efficiency measurement of respirators by laser-based particle counting method.基于激光粒子计数法的呼吸器过滤效率测量
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EClinicalMedicine. 2020 Apr 3;21:100329. doi: 10.1016/j.eclinm.2020.100329. eCollection 2020 Apr.
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