Department of Dermatology, Bispebjerg University Hospital, Copenhagen, Denmark.
Skin Res Technol. 2022 Jan;28(1):180-186. doi: 10.1111/srt.13102. Epub 2021 Nov 10.
Positive influence of the sun on psoriasis is a common assumption in dermatology. Other season-related factors such as mental health may interfere. However, the role of seasonal effects on psoriasis needs to be clarified. This review aims to systematically analyze the literature on seasonal variation on psoriasis with emphasis on Northern and Central Europe representing temperate climate conditions.
Enrolled literature was identified through PubMed, EMBASE, and BIOSIS. An additional manual search of old reports before the introduction of efficient modern therapies, which can interfere with the spontaneous disease, was performed.
Thirteen studies were enrolled. About 50% of psoriasis patients were stable and showed no seasonal difference between seasons. Approximately 30% improved in summer, and 20% performed better in winter, some with marked summer worsening. European results matched international reports from different continents and hemispheres with climate extremes. The psychological effects could not be ruled out.
About 50% of psoriasis patients experience a season-independent disease, however, with a subset of patients who do better in summer. Others again do better in winter, with a few of these having marked worsening in warm periods. Individual season-related activity records should be paid proper attention to when considering light therapy or climatotherapy as a treatment.
阳光对银屑病的积极影响是皮肤科的一个常见假设。其他与季节相关的因素，如心理健康，可能会产生干扰。然而，银屑病的季节性影响的作用仍需阐明。本综述旨在系统分析银屑病季节性变化的文献，重点关注代表温带气候条件的北欧和中欧。
通过 PubMed、EMBASE 和 BIOSIS 确定纳入的文献。此外，还对引入高效现代疗法之前的旧报告进行了手工检索，这些疗法可能会干扰自发疾病。
共纳入 13 项研究。约 50%的银屑病患者病情稳定，各季节之间无明显差异。约 30%的患者夏季改善，20%的患者冬季改善，部分患者夏季病情明显加重。欧洲的结果与来自不同大陆和半球的国际报告相匹配，这些报告存在极端气候。心理影响不能排除。
约 50%的银屑病患者病情不受季节影响，但有一部分患者夏季病情好转。还有一部分患者冬季病情好转，其中少数患者在温暖期病情明显恶化。在考虑光疗或气候疗法作为治疗方法时，应适当关注个体与季节相关的活动记录。
