Department of Pharmacology and Toxicology, Unaizah College of Pharmacy, Qassim University, Saudi Arabia.
Drug Res (Stuttg). 2022 Mar;72(3):148-155. doi: 10.1055/a-1658-3036. Epub 2021 Nov 10.
This research reveals that drugs and chemicals poisoning have been reported to have severe and fetal side effects on health provided by doctors in statistics and periodical records. This work aimed to explore the interaction among drug and chemical poisoning patterns concerning risk factors, especially gender, age, exposure circumstances, and outcomes in the Makkah region. A retrospective analysis was of clinical drug and chemical poisoning cases (2014-2015). The data were retrieved from the Department of Environmental and Occupational Health, Ministry of Health, Makkah, Saudi Arabia. The Saudi Arabia Ministry of Health received 1216 reports of drug and chemical poisoning during 2014-2015 in Makkah. This study has found that, the most affected gender was that of males (65%). The most affected age category with drug poisoning was over 15 years old (67%), but under 5 years for chemical poisoning (60%). The majority of drug poisoning cases are unknown drugs (42%), which accidental poisoning was a minority compared with other drug causes (27%). Chemical poisoning accidents were the majority causes of the recorded cases (63%). We reported healthy recovered without complications for most patients from drug and chemical poisoning (85-95%). Antidotes were administered in only (5%) of cases, and fatalities were reported (0.5% of cases). We have shown a flagrant increase in the number of people poisoned by drugs and chemical agents during 2015. Increases poisoning cases involved both genders and all studied age categories, especially males over 15 years up to 25 (drugs) and < 5 years (chemicals). Most cases were accidental (chemicals) and reported healthy recovery for most patients.
这项研究表明,医生在统计和期刊记录中报告了药物和化学中毒对健康的严重和胎儿影响。本工作旨在探讨药物和化学中毒模式之间的相互作用,特别是与风险因素有关的性别、年龄、暴露情况和结局,研究地点在麦加地区。对临床药物和化学中毒病例(2014-2015 年)进行了回顾性分析。这些数据是从沙特阿拉伯麦加卫生部环境和职业健康司检索到的。2014-2015 年期间,沙特阿拉伯卫生部收到了 1216 份药物和化学中毒报告。本研究发现,受影响最大的性别是男性(65%)。药物中毒的最主要年龄段是 15 岁以上(67%),而化学中毒的最主要年龄段是 5 岁以下(60%)。大多数药物中毒是未知药物(42%),与其他药物原因相比,意外中毒是少数(27%)。化学中毒事故是记录病例的主要原因(63%)。我们报告大多数药物和化学中毒患者(85-95%)健康恢复,没有并发症。只有(5%)的病例使用了解毒剂,有(0.5%)的病例报告了死亡。我们发现,2015 年因药物和化学制剂中毒的人数明显增加。中毒病例涉及男女两性和所有研究年龄组,尤其是 15 岁以上至 25 岁的男性(药物)和<5 岁的儿童(化学物质)。大多数病例是意外(化学物质),大多数患者报告健康恢复。