Department of Anorectal, The Third Affiliated Hospital of Liaoning University of Traditional Chinese Medicine, Shenyang 110005, Liaoning, China.
Department of Anorectal Surgery, Beijing Mayinglong Changqing Anorectal Hospital, Beijing 100195, China.
J Healthc Eng. 2021 Nov 1;2021:9024919. doi: 10.1155/2021/9024919. eCollection 2021.
Functional constipation is relatively common in both adults and children, exhibiting similar symptoms. However, there are significant differences in the epidemiology, symptomatology, pathophysiology, diagnostic tests, and treatment management of functional constipation by age. The treatment of functional constipation is generally based on lifestyle interventions, pelvic floor interventions, and pharmacotherapy. Pharmacological treatment is popular as the most direct and effective modality, especially the herbal preparations (e.g., Shouhui Tongbian capsule), which are popular for their lower toxic side effects and less physiological reactions. In our clinical study, patients with functional constipation who took Shouhui Tongbian capsules for a longer period of time showed significantly better improvement than those who took them for a shorter period of time ( < 0.001). Relative to the duration of the disease, the improvement effect was higher in patients with short duration of the disease than in patients with long duration of the disease ( < 0.001). What's more, Shouhui Tongbian capsule had a regulating effect on intestinal flora, and the regulating effect was stronger in patients with a shorter disease duration.
功能性便秘在成人和儿童中均较为常见，表现出相似的症状。然而，功能性便秘在流行病学、症状学、病理生理学、诊断试验和治疗管理方面存在显著的年龄差异。功能性便秘的治疗通常基于生活方式干预、盆底干预和药物治疗。药物治疗因其最直接和有效的方式而广受欢迎，尤其是草药制剂（例如，首荟通便胶囊），因其毒性副作用较低和生理反应较少而受到青睐。在我们的临床研究中，服用首荟通便胶囊时间较长的功能性便秘患者的改善情况明显优于服用时间较短的患者（<0.001）。与疾病持续时间相比，病程较短的患者的改善效果更高（<0.001）。此外，首荟通便胶囊对肠道菌群具有调节作用，且在病程较短的患者中调节作用更强。
