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Fibroadenoma of the breast showing a translocation (6;14), a ring chromosome and two markers involving parts of chromosome 11.

作者信息

Leuschner E, Meyer-Bolte K, Caselitz J, Bartnitzke S, Bullerdiek J

机构信息

Center of Human Genetics and Genetic Counselling, University of Bremen, Germany.

出版信息

Cancer Genet Cytogenet. 1994 Sep;76(2):145-7. doi: 10.1016/0165-4608(94)90466-9.

DOI:10.1016/0165-4608(94)90466-9
PMID:7923065
Abstract

The cytogenetic findings of a recurrent fibroadenoma of a 25-year-old woman are reported. Of 58 metaphases karyotyped after G-banding, 27 showed an apparently normal karyotype and 31 the karyotype 48,XX,del(6)(q21),r(11)(?) + der(11)x2,der(14)t(6;14)(q21;q32). By fluorescence in situ hybridization studies using a chromosome 11 specific painting probe, we were able to show that the two marker chromosomes and the ring contained chromosome 11 DNA.

摘要

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