Department of Community Nutrition, School of Nutrition and Food Science, Food Security Research Center, Isfahan University of Medical Sciences, Isfahan, Iran.
Isfahan Neurosciences Research Center, Alzahra Hospital, Isfahan University of Medical Sciences, Isfahan, Iran.
Br J Nutr. 2022 Oct 28;128(8):1535-1544. doi: 10.1017/S000711452100444X. Epub 2021 Nov 12.
The relationship between the Dietary Approaches to Stop Hypertension (DASH) diet and clinical, quality of life and mental health outcomes in migraine is unknown. To address this knowledge gap, we conducted a parallel-group, randomised controlled trial to evaluate the effect of the DASH diet on these health outcomes in women with migraine. Of 102 eligible women (20-50 years), fifty one randomised to the DASH and fifty one to the usual dietary advice (control) groups completed a 12-week intervention. The DASH diet was designed using a 7-d menu cycle to provide 15-20 % of total daily energy requirements from proteins, 25-30 % from fats and 55-60 % from carbohydrates. Dietary records and serum vitamin C levels were used to assess women's compliance with the DASH diet. The clinical symptoms of migraine (i.e., frequency, duration and severity) and quality of life and mental health (i.e., depression, anxiety and stress) outcomes were assessed in groups pre-and post-intervention. We observed greater decreases in the frequency (-3·00 . -1·40, = 0·025) and severity (-1·76 . -0·59, < 0·001) of migraine in the DASH . control group post-intervention. Similarly, the DASH group exhibited a tendency towards greater decreases in migraine duration (-0·58 . -0·33 d, = 0·053) and had lower scores of depression (-4·50 . -2·73, = 0·019) and stress (-5·84 . -2·98, = 0·011) . controls. However, the quality of life and anxiety outcomes remained comparable in groups post-intervention. Together, evidence supports the benefits of the DASH diet on improving migraine health outcomes in reproductive-aged women. Further research is needed to confirm our findings.
DASH 饮食与偏头痛的临床、生活质量和心理健康结局之间的关系尚不清楚。为了填补这一知识空白，我们开展了一项平行组随机对照试验，以评估 DASH 饮食对偏头痛女性这些健康结局的影响。在 102 名符合条件的女性（20-50 岁）中，51 名随机分配到 DASH 组，51 名随机分配到常规饮食建议（对照组）组，完成了 12 周的干预。DASH 饮食是使用 7 天菜单周期设计的，以提供 15-20%的总能量需求来自蛋白质，25-30%来自脂肪，55-60%来自碳水化合物。饮食记录和血清维生素 C 水平用于评估女性对 DASH 饮食的依从性。在干预前后，评估偏头痛的临床症状（即频率、持续时间和严重程度）以及生活质量和心理健康（即抑郁、焦虑和压力）结局。我们观察到，在干预后，DASH-对照组偏头痛的频率（-3.00 ，-1.40 ，= 0.025）和严重程度（-1.76 ，-0.59 ，< 0.001）均有更大的降低。同样，DASH 组偏头痛持续时间（-0.58 ，-0.33 d ，= 0.053）也有降低的趋势，抑郁评分（-4.50 ，-2.73 ，= 0.019）和压力评分（-5.84 ，-2.98 ，= 0.011）也更低。然而，干预后两组的生活质量和焦虑结局仍然相当。总的来说，证据支持 DASH 饮食对改善生育期女性偏头痛健康结局的益处。需要进一步的研究来证实我们的发现。
