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老年患者连续股骨近端骨折的危险因素及后果分析

Analysis of Risk Factors and Consequences of Consecutive Proximal Femur Fractures in Elderly Patients.

作者信息

Gurusinghe Suranga, M Navaratnam Devaraj, Weerasinghe Konara, Gopinath Girish, Uzoigwe Chika, Joachim Theophilus

机构信息

Trauma and Orthopedics, Pilgrim Hospital, Boston, GBR.

出版信息

Cureus. 2021 Oct 6;13(10):e18527. doi: 10.7759/cureus.18527. eCollection 2021 Oct.

Abstract

Background Proximal femur fracture (PFF) carries significant morbidity, mortality, and cost implications to the health system. Subsequent contralateral fracture further decreases patient performance and increases the healthcare burden. This study aimed to identify and evaluate potential risk factors for consecutive PFF. Methodology Pilgrim Hospital PFF database from 2012 to 2019 was retrospectively analyzed. Patients over 60 years with low-energy fractures were included. Pathological and atypical fractures and polytrauma were excluded. Results There were 114 patients (4.18%) with contralateral hip fractures out of a total of 2727 PFF patients; 80% were females. The mean age was 82 years for the first hip fracture and 85 years for the second. The average time interval between fractures was 36 months. The fracture pattern was the same on both sides in 74.3% of patients (P<0.0001). Out of 53 patients with cemented hip hemiarthroplasty (CHH) on one side, 31 patients (59%) had a second CHH for the contralateral side. Likewise, out of 48 patients who had dynamic hip screw fixation during the first admission, 33 patients (69%) had the same procedure on the contralateral side too. During the two consecutive admissions, the length of hospital stay was not significantly different (P=0.30), median American Society of Anesthesiologists (ASA) grades were 3, hyponatremia increased from 25% to 29% (P=0.5), mean decline in abbreviated mental test score (AMTS) was 0.4, deterioration of Clinical Frailty Score and Charlson morbidity index were from 4.5 to 5.9 (P<0.0001), and from 5.4 to 6.1, respectively, and institutional residency was increased from 23 to 46 (P>0.0014). Conclusion The similarity of fracture pattern bilaterally requiring similar surgical procedures is comparable with other literature. Even though there is minimal or no change in the ASA, AMTS, and hospital stay between the two admissions, there is a significant decline in clinical frailty, mobility status, and an increase in residential dependency following a subsequent fracture. Our findings demonstrate the importance of emphasizing secondary preventive measures to prevent a consecutive fracture.

摘要

背景 股骨近端骨折(PFF)对健康系统具有重大的发病率、死亡率及成本影响。随后发生的对侧骨折会进一步降低患者的身体机能,并增加医疗负担。本研究旨在识别和评估连续发生PFF的潜在风险因素。方法 对2012年至2019年朝圣者医院的PFF数据库进行回顾性分析。纳入60岁以上的低能量骨折患者。排除病理性骨折、非典型骨折和多发伤患者。结果 在2727例PFF患者中,有114例(4.18%)发生了对侧髋部骨折;其中80%为女性。首次髋部骨折的平均年龄为82岁,第二次为85岁。两次骨折之间的平均时间间隔为36个月。74.3%的患者双侧骨折类型相同(P<0.0001)。在一侧接受骨水泥型半髋关节置换术(CHH)的53例患者中,31例(59%)对侧也接受了第二次CHH手术。同样,在首次入院时接受动力髋螺钉固定的48例患者中,33例(69%)对侧也进行了相同的手术。在连续两次入院期间,住院时间无显著差异(P=0.30),美国麻醉医师协会(ASA)分级中位数为3级,低钠血症从25%增至29%(P=0.5),简易精神状态检查表(AMTS)平均下降0.4分,临床衰弱评分和查尔森发病指数分别从4.5恶化至5.9(P<0.0001)和从5.4恶化至6.1,机构居住率从23增至46(P>0.0014)。结论 双侧骨折类型相似且需要相似手术的情况与其他文献报道相当。尽管两次入院之间ASA、AMTS和住院时间变化很小或没有变化,但后续骨折后临床衰弱、活动能力显著下降,居住依赖性增加。我们的研究结果表明强调二级预防措施以预防连续骨折的重要性。

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本文引用的文献

1
Short-term risk factors for a second hip fracture in a UK population.英国人群中第二次髋部骨折的短期风险因素。
Eur J Orthop Surg Traumatol. 2019 Jul;29(5):1055-1060. doi: 10.1007/s00590-019-02412-8. Epub 2019 Mar 12.
3
Evaluation of Risk Factors for Second Hip Fractures in Elderly Patients.老年患者二次髋部骨折危险因素评估
J Clin Med Res. 2018 Mar;10(3):217-220. doi: 10.14740/jocmr3287w. Epub 2018 Jan 26.
4
Second Hip Fracture: Incidence, Trends, and Predictors.第二次髋部骨折:发生率、趋势和预测因素。
Calcif Tissue Int. 2018 Jun;102(6):619-626. doi: 10.1007/s00223-017-0364-2. Epub 2017 Nov 20.

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