Suppr超能文献

血清白蛋白水平对自发性蛛网膜下腔出血患者入院时的预测价值。

Predictive Value of the Serum Albumin Level on Admission in Patients With Spontaneous Subarachnoid Hemorrhage.

作者信息

Shang Feng, Zhao Hao, Cheng Weitao, Qi Meng, Wang Ning, Qu Xin

机构信息

Department of Neurosurgery, Xuanwu Hospital of Capital Medical University, Beijing, China.

出版信息

Front Surg. 2021 Oct 26;8:719226. doi: 10.3389/fsurg.2021.719226. eCollection 2021.

Abstract

To determine the effect of the serum albumin level on admission in patients with spontaneous subarachnoid hemorrhage (SAH). A total of 229 patients with SAH were divided into control and hypoalbuminemia groups. The serum albumin levels were measured. The data, including age, gender, co-existing medical conditions, risk factors, Hunt-Hess (H-H) grade on admission, Glasgow coma score (GCS) on admission, complications during hospitalizations, length of hospital stay, length of intensive care unit (ICU) stay, in-hospital mortality, survival rate, outcome at discharge, and the 6-month follow-up outcome, were compared between the two groups. Older age, an increased number of patients who consumed an excess of alcohol, and a lower GCS on admission were findings in the hypoalbuminemia group compared to the control group ( < 0.001). The ratio of patients with H-H grade I on admission in the hypoalbuminemia group was decreased compared to the control group ( < 0.05). Patients with hypoalbuminemia were more likely to be intubated, and have pneumonia and cerebral vasospasm than patients with a normal albumin level on admission ( < 0.001). Furthermore, the length of hospital and ICU stays were longer in the hypoalbuminemia group than the control group ( < 0.001). Hypoalbuminemia on admission significantly increased poor outcomes at discharge ( < 0.001). The number of patients with severe disability was increased and the recovery rate was decreased with respect to in-hospital outcomes in the hypoalbuminemia group than the control group ( < 0.001). Hypoalbuminemia was shown to be associated with a poor prognosis in patients with SAH.

摘要

为确定血清白蛋白水平对自发性蛛网膜下腔出血(SAH)患者入院时的影响。总共229例SAH患者被分为对照组和低白蛋白血症组。测量血清白蛋白水平。比较两组之间的数据,包括年龄、性别、并存的内科疾病、危险因素、入院时的Hunt-Hess(H-H)分级、入院时的格拉斯哥昏迷评分(GCS)、住院期间的并发症、住院时间、重症监护病房(ICU)住院时间、院内死亡率、生存率、出院结局以及6个月随访结局。与对照组相比,低白蛋白血症组的患者年龄更大、饮酒过量的患者数量更多、入院时的GCS更低(P<0.001)。与对照组相比,低白蛋白血症组入院时H-H I级患者的比例降低(P<0.05)。与入院时白蛋白水平正常的患者相比,低白蛋白血症患者更有可能接受插管,并且发生肺炎和脑血管痉挛(P<0.001)。此外,低白蛋白血症组的住院时间和ICU住院时间比对照组更长(P<0.001)。入院时的低白蛋白血症显著增加出院时的不良结局(P<0.001)。与对照组相比,低白蛋白血症组院内结局中重度残疾患者数量增加且恢复率降低(P<0.001)。结果显示,低白蛋白血症与SAH患者的预后不良相关。

相似文献

引用本文的文献

本文引用的文献

1
Aneurysmal Subarachnoid Hemorrhage: the Last Decade.动脉瘤性蛛网膜下腔出血:过去十年
Transl Stroke Res. 2021 Jun;12(3):428-446. doi: 10.1007/s12975-020-00867-0. Epub 2020 Oct 19.
4
Preclinical efficacy of human Albumin in subarachnoid hemorrhage.人白蛋白在蛛网膜下腔出血中的临床前疗效
Neuroscience. 2017 Mar 6;344:255-264. doi: 10.1016/j.neuroscience.2016.12.033. Epub 2016 Dec 28.
5
Spontaneous subarachnoid haemorrhage.自发性蛛网膜下腔出血。
Lancet. 2017 Feb 11;389(10069):655-666. doi: 10.1016/S0140-6736(16)30668-7. Epub 2016 Sep 13.
9
Aneurysmal Subarachnoid Hemorrhage.动脉瘤性蛛网膜下腔出血
J Neurosurg Anesthesiol. 2015 Jul;27(3):222-40. doi: 10.1097/ANA.0000000000000130.

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验