Nguyen Van Tuan, Phan Ha Linh, Hoang Thi Minh, Dam Thi Phuong Lan, Ho Thi Hang, Huynh Quang Thuan
Internal Medicine Department.
Biochemistry and Hematology Department, Vinh Medical University, Nghe An.
Cardiovasc Endocrinol Metab. 2021 Jun 9;10(4):210-214. doi: 10.1097/XCE.0000000000000251. eCollection 2021 Dec.
The ankle-brachial index (ABI) is a fast, simple, noninvasive method that provides accurate results in the early diagnosis of peripheral artery disease. Microalbuminuria is considered a predictor of renal and cardiovascular complications in patients with diabetes. This study was conducted to determine the correlation between ABI and microalbuminuria with certain risk factors in patients with type 2 diabetes.
A cross-sectional descriptive study was performed on 62 inpatients with type 2 diabetes. All patients were measured for ABI as well as microalbuminuria, HbA1c, glucose and lipidemia in the blood.
The study results showed that in patients with dyslipidemia, the risk of having microalbuminuria (+) increased 5.7 times and ABI ≤0.90 increased 8.6 times ( = 0.004 and 0.021, respectively). Fasting blood glucose >7.2 mmol/L had 5.7 times higher microalbuminuria (+) risk and 8.6 times higher ABI ≤0.90 ( = 0.004 and 0.021, respectively). Patients with HbA1c ≥7% were 2.9 times more likely to have microalbuminuria (+) and ABI ≤0.90 ( = 0.043 and 0.048, respectively).
Peripheral vascular disease risk factors such as hypertension, dyslipidemia and waist circumference and the effectiveness of fasting blood glucose and HbA1c control increased the risk of high microalbuminuria and ABI in patients with type 2 diabetes.
踝臂指数(ABI)是一种快速、简单、无创的方法,在周围动脉疾病的早期诊断中能提供准确结果。微量白蛋白尿被认为是糖尿病患者肾脏和心血管并发症的预测指标。本研究旨在确定2型糖尿病患者中ABI与微量白蛋白尿之间的相关性以及某些危险因素。
对62例2型糖尿病住院患者进行了横断面描述性研究。所有患者均测量了ABI、微量白蛋白尿、糖化血红蛋白(HbA1c)、血糖和血脂。
研究结果显示,在血脂异常患者中,微量白蛋白尿(+)的风险增加5.7倍,ABI≤0.90的风险增加8.6倍(分别为P = 0.004和0.021)。空腹血糖>7.2 mmol/L时,微量白蛋白尿(+)的风险高5.7倍,ABI≤0.90的风险高8.6倍(分别为P = 0.004和0.021)。糖化血红蛋白≥7%的患者发生微量白蛋白尿(+)和ABI≤0.90的可能性分别高2.9倍(分别为P = 0.043和0.048)。
高血压、血脂异常和腰围等周围血管疾病危险因素以及空腹血糖和糖化血红蛋白控制效果增加了2型糖尿病患者微量白蛋白尿高风险和ABI的风险。