Department of Chemical Engineering and Center for Soft Matter and Biological Physics, Virginia Tech, Blacksburg, Virginia 24061, United States.
Department of Biological Sciences, Virginia Tech, Blacksburg, Virginia 24061, United States.
ACS Appl Mater Interfaces. 2021 Nov 24;13(46):54706-54714. doi: 10.1021/acsami.1c15505. Epub 2021 Nov 12.
Antimicrobial coatings are one method to reduce the spread of microbial diseases. Transparent coatings preserve the visual properties of surfaces and are strictly necessary for applications such as antimicrobial cell phone screens. This work describes transparent coatings that inactivate microbes within minutes. The coatings are based on a polydopamine (PDA) adhesive, which has the useful property that the monomer can be sprayed, and then the monomer polymerizes in a conformal film at room temperature. Two coatings are described (1) a coating where PDA is deposited first and then a thin layer of copper is grown on the PDA by electroless deposition (PDA/Cu) and (2) a coating where a suspension of CuO particles in a PDA solution is deposited in a single step (PDA/CuO). In the second coating, PDA menisci bind CuO particles to the solid surface. Both coatings are transparent and are highly efficient in inactivating microbes. PDA/Cu kills >99.99% of and 99.18% of methicillin-resistant (MRSA) in only 10 min and inactivates 99.98% of SARS-CoV-2 virus in 1 h. PDA/CuO kills 99.94% of and 96.82% of MRSA within 10 min and inactivates 99.88% of SARS-CoV-2 in 1 h.
抗菌涂层是减少微生物疾病传播的一种方法。透明涂层保留了表面的视觉特性，对于抗菌手机屏幕等应用来说是严格必需的。这项工作描述了可以在几分钟内使微生物失活的透明涂层。这些涂层基于聚多巴胺 (PDA) 粘合剂，具有有用的特性，即单体可以喷涂，然后单体在室温下在一个保形膜中聚合。描述了两种涂层：(1) 首先沉积 PDA，然后通过化学镀在 PDA 上生长一层薄薄的铜的涂层（PDA/Cu），和 (2) 将氧化铜颗粒在 PDA 溶液中的悬浮液沉积在一个步骤中的涂层（PDA/CuO）。在第二种涂层中，PDA 弯月面将 CuO 颗粒绑定到固体表面。两种涂层都是透明的，并且在使微生物失活方面非常有效。PDA/Cu 在 10 分钟内杀死了超过 99.99%的 和 99.18%的耐甲氧西林金黄色葡萄球菌 (MRSA)，在 1 小时内灭活了 99.98%的 SARS-CoV-2 病毒。PDA/CuO 在 10 分钟内杀死了超过 99.94%的 和 96.82%的 MRSA，在 1 小时内灭活了 99.88%的 SARS-CoV-2。
