Karak A K, Mathur M, Choudhry V P
Leuk Res. 1987;11(8):693-7. doi: 10.1016/0145-2126(87)90004-x.
Tritiated thymidine labeling index (LI) was determined in 25 unselected children with cytochemically proved ALL, at various stages of the disease. All the cases were treated by a uniform therapeutic protocol. Pretreatment LI determined in 15 cases showed an inverse correlation with the duration of first complete remission. LI was also studied during remission in 23 patients. Six out of these 23 patients relapsed within subsequent 90 days, while the rest continued to be in remission. Mean LI of the nonerythroid cells in later group of patients was found to be significantly higher than that of the patients who relapsed.
在25例未经挑选、经细胞化学证实为急性淋巴细胞白血病（ALL）的不同疾病阶段的儿童中，测定了氚标记胸腺嘧啶核苷标记指数（LI）。所有病例均采用统一的治疗方案进行治疗。对15例病例进行的预处理LI测定显示，其与首次完全缓解的持续时间呈负相关。还对23例患者缓解期的LI进行了研究。这23例患者中有6例在随后的90天内复发，其余患者持续缓解。发现后一组患者非红系细胞的平均LI显著高于复发患者。
