Saini Gia, Segaran Nicole, Mayer Joseph L, Saini Aman, Albadawi Hassan, Oklu Rahmi
Division of Vascular and Interventional Radiology, Laboratory for Patient Inspired Engineering, Mayo Clinic, Phoenix, AZ 85054, USA.
3D Innovations Laboratory, Support Services Building, Mayo Clinic, Phoenix, AZ 85054, USA.
J Clin Med. 2021 Oct 26;10(21):4966. doi: 10.3390/jcm10214966.
Regenerative medicine is an emerging field that centers on the restoration and regeneration of functional components of damaged tissue. Tissue engineering is an application of regenerative medicine and seeks to create functional tissue components and whole organs. Using 3D printing technologies, native tissue mimics can be created utilizing biomaterials and living cells. Recently, regenerative medicine has begun to employ 3D bioprinting methods to create highly specialized tissue models to improve upon conventional tissue engineering methods. Here, we review the use of 3D bioprinting in the advancement of tissue engineering by describing the process of 3D bioprinting and its advantages over other tissue engineering methods. Materials and techniques in bioprinting are also reviewed, in addition to future clinical applications, challenges, and future directions of the field.
再生医学是一个新兴领域，其核心是受损组织功能成分的修复和再生。组织工程是再生医学的一种应用，旨在创建功能性组织成分和完整器官。利用3D打印技术，可以使用生物材料和活细胞创建天然组织模拟物。最近，再生医学已开始采用3D生物打印方法来创建高度专业化的组织模型，以改进传统的组织工程方法。在此，我们通过描述3D生物打印的过程及其相对于其他组织工程方法的优势，来综述3D生物打印在组织工程进展中的应用。除了该领域未来的临床应用、挑战和未来方向外，还综述了生物打印中的材料和技术。
