Wynne L C, Cole R E, Perkins P
Schizophr Bull. 1987;13(3):463-76. doi: 10.1093/schbul/13.3.463.
The University of Rochester Child and Family Study (URCAFS) is a risk research program concerned with cross-sectional and developmental relationships among three areas: parental psychopathology and health, family system functioning and dysfunctioning, and child psychopathology and health. The preliminary findings indicate that both parental psychopathology and family variables predict significantly to independent measures of school functioning of index sons during their childhood and early adolescence. Although the offspring have not yet reached the age of major risk for schizophrenia, 52 percent of the families have one or more offspring either in psychiatric treatment or for whom treatment had been recommended.
罗切斯特大学儿童与家庭研究（URCAFS）是一项风险研究项目，关注三个领域之间的横断面关系和发展关系：父母精神病理学与健康、家庭系统功能正常与功能失调，以及儿童精神病理学与健康。初步研究结果表明，父母精神病理学和家庭变量都能显著预测指标儿子在童年和青春期早期学校功能的独立测量值。尽管这些后代尚未达到精神分裂症的主要风险年龄，但52%的家庭有一个或多个后代正在接受精神科治疗或已被建议接受治疗。
