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STK3 promotes gastric carcinogenesis by activating Ras-MAPK mediated cell cycle progression and serves as an independent prognostic biomarker.

作者信息

Chen Bonan, Chan Wai Nok, Mui Chun Wai, Liu Xiaoli, Zhang Jinglin, Wang Yifei, Cheung Alvin H K, Chan Aden K Y, Chan Ronald C K, Leung Kam Tong, Dong Yujuan, Pan Yi, Ke Huixing, Liang Li, Zhou Zhaocai, Wong Chi Chun, Wu William K K, Cheng Alfred S L, Yu Jun, Lo Kwok Wai, To Ka Fai, Kang Wei

机构信息

Department of Anatomical and Cellular Pathology, State Key Laboratory of Translational Oncology, Prince of Wales Hospital, The Chinese University of Hong Kong, Shatin, Hong Kong, SAR, People's Republic of China.

Institute of Digestive Disease, State Key Laboratory of Digestive Disease, The Chinese University of Hong Kong, Hong Kong, SAR, People's Republic of China.

出版信息

Mol Cancer. 2021 Nov 12;20(1):147. doi: 10.1186/s12943-021-01451-2.

DOI:10.1186/s12943-021-01451-2
PMID:
34772410
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8588685/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c9c6/8588685/5feaf1f8b33d/12943_2021_1451_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c9c6/8588685/e2f40193944c/12943_2021_1451_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c9c6/8588685/319132e75279/12943_2021_1451_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c9c6/8588685/5feaf1f8b33d/12943_2021_1451_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c9c6/8588685/e2f40193944c/12943_2021_1451_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c9c6/8588685/319132e75279/12943_2021_1451_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c9c6/8588685/5feaf1f8b33d/12943_2021_1451_Fig3_HTML.jpg

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Cancer Cell. 2021 Aug 9;39(8):1115-1134.e12. doi: 10.1016/j.ccell.2021.06.016. Epub 2021 Jul 21.
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