Department of Respiratory Medicine, University of Occupational and Environmental Health, Japan.
Department of Pathology, University of Occupational and Environmental Health, Japan.
Intern Med. 2022 Jun 15;61(12):1881-1886. doi: 10.2169/internalmedicine.8330-21. Epub 2021 Nov 13.
An 82-year-old Japanese man with idiopathic pulmonary fibrosis (IPF) experienced dyspnea after using a waterproofing spray in a closed room. He presented with hypoxemia and his chest computed tomography showed additive bilateral diffuse ground-glass attenuation on fibrosis, which was diagnostic of an acute exacerbation of IPF (AE-IPF). Combined treatment with high-dose corticosteroids and immunosuppressants were ineffective, and he later died of respiratory failure. Autopsy findings showed diffuse alveolar damage with honeycombing. His medical history and autopsy histopathology suggested AE-IPF caused by the inhalation of a waterproofing spray.
一位 82 岁的日本男性，患有特发性肺纤维化（IPF），在密闭房间内使用防水喷雾后出现呼吸困难。他表现出低氧血症，胸部计算机断层扫描显示纤维化的双侧弥漫性磨玻璃样混浊加重，这是特发性肺纤维化急性加重（AE-IPF）的诊断依据。大剂量皮质类固醇和免疫抑制剂联合治疗无效，后来他因呼吸衰竭而死亡。尸检结果显示弥漫性肺泡损伤伴蜂窝肺。他的病史和尸检组织病理学提示 AE-IPF 是由吸入防水喷雾引起的。
Zotero 插件
