Yamashita Yoshiyuki, Joo Kunihiko, Okamoto Koji, Nakata Yusuke, Ochiai Yoshie, Tokunaga Shigehiko
Department of Cardiovascular Surgery, Japan Community Healthcare Organization Kyushu Hospital, Kitakyushu, Japan.
Department of Cardiovascular Surgery, Japan Community Healthcare Organization Kyushu Hospital, Kitakyushu, Japan.
Ann Vasc Surg. 2022 Apr;81:121-128. doi: 10.1016/j.avsg.2021.09.043. Epub 2021 Nov 12.
This study investigated the impact of aortic diameter on late aortic dilation of the residual dissected aorta after tear-oriented aortic replacement for acute DeBakey type I aortic dissection.
Of 133 patients who underwent aortic replacement for acute DeBakey type I/II aortic dissection between 2008 and 2019, 45 patients with a residual dissected aorta after surgery for acute DeBakey type I aortic dissection and who underwent computed tomography at predischarge and after 1 year were retrospectively assessed. The aortic diameter and false lumen area were measured at 3 levels: the maximal aortic site, seventh thoracic vertebra, and celiac axis. Multivariable Cox regression analysis was employed to identify the predictors of late aortic dilation, defined as an aortic growth rate of ≥5 mm/year or a maximal aortic diameter of ≥55 mm.
During a median follow-up of 75 [range: 13-152] months, 6 patients (5 men; mean age: 57 ± 14 years) experienced aortic dilation. All 6 patients had the maximal aortic diameter between the distal aortic arch and seventh thoracic vertebra level at the last computed tomography. Multivariable Cox regression analysis showed that the predischarge maximal aortic diameter was an independent determinant of late aortic dilation (hazard ratio: 2.28/mm, 95% confidence interval: 1.10-5.86).
Predischarge maximal aortic diameter is a significant predictor of late aortic dilation in patients with a residual dissected aorta after tear-oriented surgical repair of acute DeBakey type I aortic dissection.
本研究调查了在针对急性DeBakey I型主动脉夹层进行撕裂方向主动脉置换术后,主动脉直径对残余夹层主动脉晚期扩张的影响。
回顾性评估了2008年至2019年间因急性DeBakey I/II型主动脉夹层接受主动脉置换术的133例患者,其中45例急性DeBakey I型主动脉夹层手术后有残余夹层主动脉且在出院前和1年后接受了计算机断层扫描的患者。在三个层面测量主动脉直径和假腔面积:主动脉最大部位、第七胸椎和腹腔干。采用多变量Cox回归分析来确定晚期主动脉扩张的预测因素,晚期主动脉扩张定义为主动脉生长速率≥5mm/年或最大主动脉直径≥55mm。
在中位随访75 [范围:13 - 152]个月期间,6例患者(5例男性;平均年龄:57±14岁)出现主动脉扩张。在最后一次计算机断层扫描时,所有6例患者的最大主动脉直径均位于主动脉弓远端和第七胸椎水平之间。多变量Cox回归分析显示,出院前最大主动脉直径是晚期主动脉扩张的独立决定因素(风险比:2.28/mm,95%置信区间:1.10 - 5.86)。
在针对急性DeBakey I型主动脉夹层进行撕裂方向手术修复后有残余夹层主动脉的患者中,出院前最大主动脉直径是晚期主动脉扩张的重要预测因素。