State Key Laboratory of Applied Organic Chemistry, College of Chemistry and Chemical Engineering, Lanzhou University, Lanzhou 730000, P. R. China.
State Key Laboratory of Veterinary Etiological Biology, College of Veterinary Medicine, Lanzhou University, Lanzhou 730000, P. R. China.
Chem Commun (Camb). 2021 Dec 3;57(96):12914-12935. doi: 10.1039/d1cc04883j.
Over the past years, impressive progress has been made in the development of organic photoredox catalytic cascade reactions without the participation of expensive and toxic transition metals under visible light irradiation. These transformations highly depend on the generation of various radical species in the photoredox catalytic cycles. Numerous chemically and biomedically valuable building blocks have been synthesized through this efficient and sustainable protocol. In this review, we highlight the recent progress in this blooming area by presenting a series of new catalytic cascade reactions mediated by organic photoredox catalysts and describe their mechanisms and applications which have appeared in the recent literature.
在过去的几年中，人们在可见光照射下无需使用昂贵且有毒的过渡金属的情况下，在开发有机光氧化还原催化级联反应方面取得了令人瞩目的进展。这些转化高度依赖于光氧化还原催化循环中各种自由基物种的生成。通过这种高效和可持续的方案，已经合成了许多具有化学和生物医学价值的构建模块。在这篇综述中，我们通过介绍一系列新的由有机光氧化还原催化剂介导的催化级联反应来突出这一蓬勃发展领域的最新进展，并描述了它们在近期文献中出现的机制和应用。
