母亲接种科兴疫苗后 COVID-19 抗体的垂直传播：一例报告。
Vertical transmission of maternal COVID-19 antibodies after CoronaVac vaccine: A case report.
机构信息
Universidade do Sul de Santa Catarina, Programa de Pós-Graduação em Ciências da Saúde, Tubarão, SC, Brasil.
Universidade do Sul de Santa Catarina, Faculdade de Medicina, Tubarão, SC, Brasil.
出版信息
Rev Soc Bras Med Trop. 2021 Nov 12;54:e0385. doi: 10.1590/0037-8682-0385-2021. eCollection 2021.
Abstract
The use of coronavirus disease 2019 RNA vaccines in pregnant women led to reports on the first cases of newborns with antibodies to sudden acute respiratory syndrome coronavirus 2 (SARS-CoV-2), a phenomenon that was unknown when using immunizations with inactivated viruses. Thus, this study aimed to report a case of passive anti-SARS-CoV-2 immunity in a newborn through immunoprophylaxis of a pregnant woman who received the CoronaVac® vaccine in the third trimester of pregnancy. Twenty-four hours after delivery, samples were collected from the newborn and screened by enzyme immunoassays, which revealed antibodies to SARS-CoV-2.
摘要
使用 2019 年冠状病毒病 RNA 疫苗在孕妇中导致了首例新生儿对严重急性呼吸综合征冠状病毒 2（SARS-CoV-2）产生抗体的报告，这是在使用灭活病毒免疫时未知的现象。因此，本研究旨在报告一例通过在妊娠晚期接受科兴疫苗（CoronaVac®）免疫的孕妇进行免疫预防，新生儿获得被动 SARS-CoV-2 免疫力的病例。分娩后 24 小时，从新生儿采集样本并通过酶免疫分析法进行筛查，显示出对 SARS-CoV-2 的抗体。
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