Third Department of Pediatrics, ATTIKON University Hospital, National and Kapodistrian University of Athens, Athens, Greece.
Hum Vaccin Immunother. 2021 Dec 2;17(12):5384-5387. doi: 10.1080/21645515.2021.1997034. Epub 2021 Nov 17.
Measles is an important vaccine preventable disease with significant morbidity and mortality. Although measles vaccine is a safe and effective vaccine available worldwide for more than 50 years, still immunization efforts have not successfully reached the WHO goal of 95% vaccination coverage. Hesitancy is especially increased amongst parents of children with chronic conditions. Contraindications for measles-containing vaccines are well defined and include history of anaphylactic reactions to neomycin, history of severe allergic reaction to previous vaccination, pregnancy, and severe immunosuppression. Concurrently, precautions for measles-containing vaccines include amongst other, history of thrombocytopenia or thrombocytopenic purpura and personal or family history of seizures of any etiology. This article aims to address misconceptions on measles vaccine safety and review data on adverse events among special groups of subjects at increased risk following measles immunization.
麻疹是一种重要的疫苗可预防疾病，具有显著的发病率和死亡率。尽管麻疹疫苗是一种安全有效的疫苗，已经在全球范围内使用了 50 多年，但免疫接种工作仍未能成功达到世界卫生组织 95%的疫苗接种覆盖率目标。对有慢性疾病的儿童的父母来说，他们对接种疫苗的犹豫情绪尤为增加。含麻疹疫苗的禁忌症有明确规定，包括对新霉素有过敏反应史、对以前接种疫苗有严重过敏史、怀孕和严重免疫抑制。同时，含麻疹疫苗的预防措施还包括血小板减少症或血小板减少性紫癜病史，以及任何病因的癫痫个人或家族史。本文旨在解决关于麻疹疫苗安全性的误解，并审查在麻疹免疫接种后有更高风险的特殊人群中不良事件的数据。
