Department of Gynecology and Obstetrics, Tianjin Medical University General Hospital, Tianjin, China.
Tianjin Key Laboratory of Female Reproductive Health and Eugenic, Department of Gynecology and Obstetrics, Tianjin Medical University General Hospital, Tianjin, China.
Front Cell Infect Microbiol. 2021 Nov 2;11:759795. doi: 10.3389/fcimb.2021.759795. eCollection 2021.
Mixed vaginitis is the simultaneous presence of at least two types of vaginitis, contributing to an abnormal vaginal milieu and leading to vaginal symptoms and signs. However, associations between symptoms and the type of mixed vaginitis have not been clearly elucidated, and research on mixed vaginitis is still in the preliminary stage. Therefore, the pathogenic mechanism of mixed vaginitis remains understudied. Mixed vaginitis generally involves the formation of mixed biofilms. The study of polymicrobial interactions and mixed biofilms will provide a new idea for the understanding of mixed vaginitis. Moreover, this review summarizes some effective management and laboratory diagnosis of mixed vaginitis to avoid inappropriate therapy, recurrence, and reinfection. It is of high clinical importance to obtain relevant clinical data to improve clinical knowledge about mixed vaginitis.
混合性阴道炎是指至少两种类型的阴道炎同时存在，导致阴道环境异常，并引起阴道症状和体征。然而，症状与混合性阴道炎类型之间的关联尚未得到明确阐明，混合性阴道炎的研究仍处于初步阶段。因此，混合性阴道炎的发病机制仍有待研究。混合性阴道炎通常涉及混合生物膜的形成。研究微生物群的相互作用和混合生物膜将为理解混合性阴道炎提供新的思路。此外，本综述总结了一些混合性阴道炎的有效管理和实验室诊断方法，以避免不适当的治疗、复发和再感染。获得相关的临床数据对于提高对混合性阴道炎的临床认识具有重要的临床意义。
