Redondo-Lopez V, Meriwether C, Schmitt C, Opitz M, Cook R, Sobel J D
Department of Internal Medicine, Wayne State University School of Medicine, Detroit, Michigan.
Sex Transm Dis. 1990 Jan-Mar;17(1):51-3.
In this study the authors reveal a high incidence of asymptomatic and symptomatic vulvovaginal yeast infection in patients with recurrent bacterial vaginosis. Symptomatic yeast vaginitis in these patients presents frequently as a mixed infection with symptoms and signs of both clinical entities being present simultaneously. The authors diagnosed vulvovaginal candidiasis in 10 (29%) out of 35 patients with a history of recurrent bacterial vaginosis; vulvovaginal candidiasis and bacterial vaginosis together were detected in 12 (34%) out of 35 women. Optimal therapeutic results usually require concomitant treatment of both candidal vaginitis and bacterial vaginosis. The lack of specificity of signs and symptoms of vaginitis mandates that women with recurrent bacterial vaginosis, for each symptomatic recurrence, be examined and evaluated by the use of simple laboratory tests to determine a specific diagnosis. Failure to appreciate the frequency of candida superinfection leads to empirical and inappropriate therapy for bacterial vaginosis.
在本研究中，作者发现复发性细菌性阴道病患者中无症状和有症状的外阴阴道念珠菌感染发生率很高。这些患者的有症状酵母菌性阴道炎常表现为混合感染，两种临床病症的症状和体征同时出现。作者在35例有复发性细菌性阴道病史的患者中诊断出10例（29%）患有外阴阴道念珠菌病；35名女性中有12例（34%）同时检测出外阴阴道念珠菌病和细菌性阴道病。最佳治疗效果通常需要同时治疗念珠菌性阴道炎和细菌性阴道病。阴道炎体征和症状缺乏特异性，这就要求复发性细菌性阴道病的女性每次出现症状复发时，都要通过简单的实验室检查进行检查和评估，以确定具体诊断。未能认识到念珠菌二重感染的频率会导致对细菌性阴道病进行经验性和不恰当的治疗。
