Graduate Program in Health Sciences, Federal University of Rio Grande do Norte, Natal, RN, Brazil.
Graduate Program in Physical Education, Federal University of Rio Grande do Norte, Natal, RN, Brazil.
Exp Gerontol. 2022 Jan;157:111628. doi: 10.1016/j.exger.2021.111628. Epub 2021 Nov 17.
There is evidence showing an inverse association between steps/day and arterial stiffness in adults. However, the relationship of steps/day and peak cadence with arterial stiffness is poorly understood in older adults. This study aimed to investigate the association between steps/day and peak cadence with arterial stiffness in older adults.
This cross-sectional study included 222 community-dwelling older adults (66 ± 5 years; 81.5% females; 70.3% with hypertension). Arterial stiffness was measured by aortic pulse wave velocity (aPWV). Steps/day and peak cadence were assessed by accelerometry. The participants were categorized according to the number of steps/day: sedentary <5000; low active 5000-7499; active 7500-9999; highly active 10,000+. Peak cadence was defined as the average of steps/day of the highest 30 min (not necessarily consecutive) for all valid days. Generalized linear models were used for data analyses.
The active (β = -0.34 m/s, 95% CI -0.60, -0.08) and highly active (β = -0.51 m/s, 95% CI -0.83, -0.20) groups had lower aPWV compared to the sedentary group. No significant difference was found between the low active group and the sedentary group (β = -0.21 m/s, 95% CI -0.46, 0.05). Every increment of 1000 steps/day was associated with a decrease of 0.05 m/s in the aPWV (95% CI -0.08, -0.02). Every increment of 10 steps/min in peak 30-min cadence was associated with a decrease of 0.05 m/s in aPWV (95% CI -0.09, -0.01).
Our findings show that easy-to-use proxies of the volume (steps/day) and intensity (peak cadence) of ambulatory behavior are inversely associated with arterial stiffness in older adults. The inverse association of steps/day and peak cadence with arterial stiffness is dose-response.
有证据表明，成年人每天的步数与动脉僵硬度呈负相关。然而，老年人每天的步数和最大步频与动脉僵硬度的关系尚不清楚。本研究旨在探讨老年人每天的步数和最大步频与动脉僵硬度的关系。
本横断面研究纳入了 222 名社区居住的老年人（66±5 岁；81.5%为女性；70.3%患有高血压）。动脉僵硬度通过主动脉脉搏波速度（aPWV）测量。每天的步数和最大步频通过加速度计评估。根据每天的步数将参与者分为以下几类：久坐组<5000 步；低活跃组 5000-7499 步；活跃组 7500-9999 步；高活跃组≥10000 步。最大步频定义为所有有效天数中最高 30 分钟（不一定连续）的平均步数/天。使用广义线性模型进行数据分析。
与久坐组相比，活跃组（β=-0.34m/s，95%CI-0.60，-0.08）和高活跃组（β=-0.51m/s，95%CI-0.83，-0.20）的 aPWV 较低。低活跃组与久坐组之间无显著差异（β=-0.21m/s，95%CI-0.46，0.05）。每天增加 1000 步，aPWV 降低 0.05m/s（95%CI-0.08，-0.02）。最大 30 分钟步频每增加 10 步/分钟，aPWV 降低 0.05m/s（95%CI-0.09，-0.01）。
我们的研究结果表明，易于使用的日常活动量（每天的步数）和强度（最大步频）指标与老年人的动脉僵硬度呈负相关。每天的步数和最大步频与动脉僵硬度的负相关呈剂量反应关系。
