College of Medicine and Health Sciences, Khalifa University, Abu Dhabi, United Arab Emirates; Association South East European Network for Medical Research-SOVE.
J Trace Elem Med Biol. 2022 Jan;69:126887. doi: 10.1016/j.jtemb.2021.126887. Epub 2021 Oct 29.
An increasing evidence suggests that vanadium compounds are novel potential drugs in the treatment of diabetes, atherosclerosis, and cancer. Vanadium has also demonstrated activities against RNA viruses and is a promising candidate for treating acute respiratory diseases. The antidiabetic, antihypertensive, lipid-lowering, cardioprotective, antineoplastic, antiviral, and other potential effects of vanadium are summarized here. Given the beneficial antihyperglycemic and antiinflammatory effects as well as the potential mechanistic link between the COVID-19 and diabetes, vanadium compounds could be considered as a complement to the prescribed treatment of COVID-19. Thus, further clinical trials are warranted to confirm these favorable effects of vanadium treatment in COVID-19 patients, which appear not to be studied yet.
越来越多的证据表明，钒化合物是治疗糖尿病、动脉粥样硬化和癌症的新型潜在药物。钒还表现出对 RNA 病毒的活性，是治疗急性呼吸道疾病的有前途的候选药物。本文总结了钒的抗糖尿病、降血压、降血脂、心脏保护、抗肿瘤、抗病毒等潜在作用。鉴于钒具有有益的降血糖和抗炎作用，以及 COVID-19 和糖尿病之间的潜在机制联系，钒化合物可以被认为是 COVID-19 规定治疗的补充。因此，需要进一步的临床试验来证实钒治疗 COVID-19 患者的这些有利效果，而这些效果似乎尚未得到研究。
