Ghosh P K, Ghosh A K, Biswas N M
Department of Physiology, University College of Science, Calcutta, India.
Andrologia. 1987 Mar-Apr;19(2):143-7. doi: 10.1111/j.1439-0272.1987.tb01873.x.
The enzyme 17 beta-hydroxysteroid dehydrogenase (17 beta-HSD) has been shown to exist biochemically and histochemically in the toad testis. A single injection of cadmium chloride (0.5 mg/toad) resulted 7 days later in reduced 17 beta-HSD activity in the testis and decreased serum testosterone with an increase in thumb pad glycogen content. It is concluded that cadmium induced changes lead to inhibition of androgen synthesis in the toad testis.
酶17β-羟类固醇脱氢酶（17β-HSD）已在生化和组织化学层面被证实存在于蟾蜍睾丸中。单次注射氯化镉（0.5毫克/只蟾蜍）7天后，睾丸中的17β-HSD活性降低，血清睾酮水平下降，同时拇指垫糖原含量增加。研究得出结论，镉诱导的变化会导致蟾蜍睾丸中雄激素合成受到抑制。
