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生活方式、儿童时期的不良环境及其对成人心血管健康的影响。

Lifestyle, inadequate environments in childhood and their effects on adult cardiovascular health.

机构信息

Universidade Federal de Santa Catarina, Florianópolis, SC, Brazil.

Universidade Estadual de Campinas, Faculdade de Ciências Médicas, Departamento de Saúde Coletiva, Campinas, SP, Brazil.

出版信息

J Pediatr (Rio J). 2022 Mar-Apr;98 Suppl 1(Suppl 1):S19-S26. doi: 10.1016/j.jped.2021.09.005. Epub 2021 Nov 19.

Abstract

OBJECTIVES

To discuss the associations between habits and environment in childhood and cardiovascular effects on adults.

SOURCE OF DATA

Search in PubMed, Scielo and Science databases, cohort or case-control studies, and systematic or scope-based reviewson the causal relationship among exposures in the pediatric age group and cardiovascular effects in adults.

SYNTHESIS OF DATA

The authors identified 41 eligible articles, which demonstrated an impact on cardiovascular health (characterized as surrogate events - structural or functional vascular alterations or left ventricular dysfunction - or clinical events - myocardial infarction, stroke or cardiovascular death) with environmental aspects (intrauterine or economically poor environment, violence, reduced life expectancy and serious infections) and habits (nutrition, physical activity and tobacco exposure). In addition to the direct and independent associations between exposures and outcomes, several traditional cardiovascular risk factors (CVRF) or family histories are also intermediate pathophysiological pathways in the described phenomena.

CONCLUSIONS

There are direct relationships between lifestyle and inadequate environments in childhood and cardiovascular effects, although the observed associations showed divergences in terms of results and interpretation. In spite of these, it is recommended to encourage healthy lifestyles and protection against childhood adverse exposures, as habit formation occurs at this age, and its relationship with CVRF since childhood has already been well established. On the other hand, the format and intensity of the stimulus must respect the social, cultural and psychological aspects of each population, aiming to obtain the best and most lasting result without generating harmful consequences for the individuals.

摘要

目的

探讨儿童时期的习惯和环境与成年人心血管效应之间的关联。

资料来源

在 PubMed、Scielo 和 Science 数据库中进行搜索,包括队列或病例对照研究以及系统或范围综述,以探讨儿科年龄段的暴露与成年人心血管效应之间的因果关系。

数据综合

作者确定了 41 篇符合条件的文章,这些文章证明了环境因素(宫内或经济贫困环境、暴力、预期寿命缩短和严重感染)和习惯(营养、体力活动和烟草暴露)对心血管健康(表现为替代事件 - 结构或功能血管改变或左心室功能障碍 - 或临床事件 - 心肌梗死、中风或心血管死亡)有影响。除了暴露与结局之间的直接和独立关联外,几种传统心血管危险因素(CVRF)或家族史也是描述现象中的中间病理生理途径。

结论

儿童时期的生活方式和不良环境与心血管效应之间存在直接关系,尽管观察到的关联在结果和解释上存在差异。尽管如此,仍建议鼓励健康的生活方式和预防儿童时期的不良暴露,因为习惯的形成发生在这个年龄段,而且它与儿童时期的 CVRF 已经得到很好的证实。另一方面,刺激的形式和强度必须尊重每个群体的社会、文化和心理方面,旨在获得最佳和最持久的结果,而不会对个体产生有害后果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/141b/9510931/6ad4a8ef95ec/gr1.jpg

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