Department of Health and Human Physiology, University of Iowa, Iowa City, IA, USA; Department of Epidemiology, University of Iowa, Iowa City, IA, USA.
Department of Health and Human Physiology, University of Iowa, Iowa City, IA, USA.
Midwifery. 2022 Jan;104:103202. doi: 10.1016/j.midw.2021.103202. Epub 2021 Nov 11.
To examine associations of objectively measured moderate-to-vigorous-intensity physical activity (MVPA) and sedentary behavior (SED) with pregnancy-specific health-related quality of life (QoL) across pregnancy trimesters.
Women (N=131, mean age 30.9 years ± 4.9) were recruited from two large health care systems in the United States. MVPA and SED were estimated using a waist-worn ActiGraph GT3X and thigh-worn activPAL3 micro, respectively, for seven days in each trimester of pregnancy. Questionnaires were administered in each trimester to assess pregnancy-specific health-related QoL using the Nausea and Vomiting of Pregnancy Specific health Related Quality of Life (NVPQoL) questionnaire. Mixed effects linear regression examined associations of MVPA and SED with the NVPQoL total score and domain-specific scores (physical symptoms, fatigue, emotions, and limitations) across trimesters.
The NVPQoL total score and domain-specific scores significantly varied across trimesters, with highest scores (indicating worse QoL) observed in the first trimester and lowest scores (indicating better QoL) in the second trimester. A 1-standard deviation (SD) increment in MVPA (16.0 min/day or 1.8%) was associated with better QoL as indicated by the lower NVPQoL total score (β=-4.06, p=0.024) and limitations score (β = -2.80, p<0.001). A 1-SD increment in SED (1.5 hr/day or 10.0%) was associated with worse QoL as indicated by the higher fatigue score (β = 0.82, p=0.041).
Pregnancy-specific health-related QoL varies across trimesters. Both lower SED, and to a greater extent higher MVPA are potential behavioral targets for improving pregnancy-specific health-related QoL.
研究妊娠各阶段中，通过客观测量得到的中等到剧烈强度的身体活动（MVPA）和久坐行为（SED）与妊娠特异性健康相关生活质量（QoL）的关联。
本研究招募了来自美国两个大型医疗保健系统的 131 名女性（平均年龄 30.9 岁±4.9 岁）。MVPA 和 SED 分别使用佩戴在腰部的 ActiGraph GT3X 和大腿上的 activPAL3 micro 进行 7 天的测量，每个孕期阶段测量一次。在每个孕期阶段，使用妊娠特异性恶心和呕吐相关生活质量问卷（NVPQoL）对妊娠特异性健康相关生活质量进行评估。混合效应线性回归分析了 MVPA 和 SED 与 NVPQoL 总分和特定领域评分（身体症状、疲劳、情绪和活动受限）在孕期各阶段的关联。
NVPQoL 总分和特定领域评分在孕期各阶段差异显著，第一孕期得分最高（表明 QoL 较差），第二孕期得分最低（表明 QoL 较好）。MVPA 每增加 1 个标准差（SD）（16.0 分钟/天或 1.8%）与较低的 NVPQoL 总分（β=-4.06，p=0.024）和活动受限评分（β=-2.80，p<0.001）相关，提示 QoL 更好。SED 每增加 1 个 SD（1.5 小时/天或 10.0%）与较高的疲劳评分（β=0.82，p=0.041）相关，提示 QoL 更差。
妊娠特异性健康相关 QoL 在孕期各阶段有所不同。SED 降低和 MVPA 增加都可能是改善妊娠特异性健康相关 QoL 的行为目标。
