Epilepsy Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
Department of Neurology, Jefferson Comprehensive Epilepsy Center, Thomas Jefferson University, Philadelphia, Pennsylvania, United States.
J Paediatr Child Health. 2022 Oct;58(10):1836-1840. doi: 10.1111/jpc.16120. Epub 2022 Jul 19.
We aimed to describe the long-term outcome with respect to symptom persistence amongst children hospitalised for COVID-19.
This was a follow-up study of 58 children and adolescents hospitalised with COVID-19. For all patients, the data were collected in a phone call to the family in December 2021 (9 months after the initial study and more than 13 months after their admission to hospital). We inquired about their current health status and obtained information, if the responding parent consented orally to participate and answer the questions.
Fifty-one children and adolescents were studied. Only five patients (10%) had persistent symptoms compatible with long-COVID; the reported symptoms include fatigue in four (8%), weakness in three (6%), exercise intolerance in two (4%) and shortness of breath in two (4%) patients. Four patients (7.8%), who did not have any symptoms of long-COVID in phase 1 of the study, reported new-onset symptoms or complaints that are potentially compatible with the diagnosis of long-COVID (weakness, myalgia, excess sputum, cough, fatigue) in the current phase.
Symptom persistence of long-COVID is infrequent amongst children hospitalised for COVID-19. Most of the symptoms of long-COVID will resolve with the passage of time and the residual symptoms are often mild and tolerable. The scientific community should carefully and clearly define long-COVID and its natural course in order to facilitate and harmonise future studies.
描述因 COVID-19 住院的儿童在症状持续方面的长期结果。
这是一项对 58 名因 COVID-19 住院的儿童和青少年进行的随访研究。对于所有患者,在 2021 年 12 月(首次研究后 9 个月,入院后 13 个月以上)通过电话与家属联系收集数据。我们询问了他们的当前健康状况,并在有回应的家长口头同意参与并回答问题的情况下获取了信息。
51 名儿童和青少年接受了研究。只有 5 名患者(10%)存在与长 COVID 相符的持续性症状;报告的症状包括 4 名(8%)患者的疲劳、3 名(6%)患者的虚弱、2 名(4%)患者的运动不耐受和 2 名(4%)患者的呼吸急促。在研究的第一阶段没有长 COVID 症状的 4 名患者,在当前阶段报告了新出现的症状或可能符合长 COVID 诊断的抱怨(虚弱、肌肉疼痛、痰液过多、咳嗽、疲劳)。
因 COVID-19 住院的儿童中,长 COVID 的症状持续性并不常见。大多数长 COVID 症状会随着时间的推移而消退,残留的症状通常较轻且可耐受。科学界应仔细、明确地定义长 COVID 及其自然病程,以促进和协调未来的研究。