Sciscent Bao Y, Eisele Caroline D, Ho Lisa, King Steven D, Jain Rohit, Golamari Reshma R
The Pennsylvania State University, College of Medicine, Hershey, Pennsylvania, USA.
Department of Hospital Medicine, Penn State Health Milton S. Hershey Medical Center, Hershey, Pennsylvania, USA.
J Community Hosp Intern Med Perspect. 2021 Nov 15;11(6):733-739. doi: 10.1080/20009666.2021.1974665. eCollection 2021.
The COVID-19 pandemic has altered innumerable lives. Although recent mass vaccinations offer a glimmer of hope, the rising death toll and new variants continue to dominate the current scenario. As we begin to understand more about SARS-CoV-2 infections, the territory of reinfections with COVID-19 remains unexplored. In this review, we will discuss several aspects of reinfection: (a) How is COVID-19 reinfection characterized? (b) Does prior literature differentiate between reinfection and reactivation? (c) What SARS-CoV-2 strains do the vaccines target and can they protect against new strains? Larger and longer timeline studies are needed to understand reinfection risks. With the ongoing distribution of the SARS-CoV-2 vaccines to provide protection, the understanding of the possibility for SARS-CoV-2 reinfection remains critical. : Centers for Disease Control: Severe acute respiratory syndrome coronavirus 2: Coronavirus disease 2019: Reverse Transcription Polymerase Chain Reaction: Post-Acute Sequelae of SARS-CoV-2 infection.
新冠疫情改变了无数人的生活。尽管近期大规模接种疫苗带来了一线希望，但不断上升的死亡人数和新变种仍主导着当前局势。随着我们对严重急性呼吸综合征冠状病毒2（SARS-CoV-2）感染的了解越来越多，新冠病毒再次感染的领域仍未得到探索。在本综述中，我们将讨论再次感染的几个方面：（a）新冠病毒再次感染的特征是什么？（b）先前的文献是否区分了再次感染和再激活？（c）疫苗针对哪些SARS-CoV-2毒株，它们能否预防新毒株？需要进行更大规模、更长时间的研究来了解再次感染风险。随着SARS-CoV-2疫苗的持续分发以提供保护，了解SARS-CoV-2再次感染的可能性仍然至关重要。：疾病控制中心：严重急性呼吸综合征冠状病毒2：冠状病毒病2019：逆转录聚合酶链反应：SARS-CoV-2感染的急性后遗症
