Department Psychiatric and Mental Health Nursing, Graduate School of Nursing, St. Luke's International University, Tokyo, Japan.
Department of Neuropsychiatry, Graduate School of Medicine, University of the Ryukyus, Okinawa, Japan.
Neuropsychopharmacol Rep. 2022 Mar;42(1):10-20. doi: 10.1002/npr2.12219. Epub 2021 Nov 22.
To describe the development and acceptability of a decision aid (DA) for chronic insomnia considering discontinuation of benzodiazepine (BZD) and benzodiazepine receptor agonist (BZRA) hypnotics, and if discontinuing, tapering with or without cognitive behavioral therapy for insomnia (CBT-I).
We reviewed relevant literature describing chronic insomnia to identify options. We used the results of the systematic review and meta-analysis conducted previously to determine the related outcomes of two options: discontinuation of BZD/BZRA hypnotics by gradual tapering alone and discontinuation of BZD/BZRA hypnotics by gradual tapering with CBT-I. We then developed a prototype of DA following the International Patient Decision Aid Standards. A mixed methods survey was conducted to assess the acceptability among patients and healthcare providers.
The prototype consisted of a description of insomnia, options of continuing or discontinuing BZD/BRZA hypnotics (if discontinuing, the options of tapering hypnotics with or without CBT-I), pros and cons of each option, and a value clarification exercise. Patients (n = 24) reported that the DA had acceptable language (79%), adequate information (71%), and well-balanced presentation (91%). Healthcare providers (n = 20) also provided favorable feedback.
We developed a DA for chronic insomnia considering discontinuation of BZD/BRZA hypnotics, which was acceptable for stakeholders. The developed DA was designed to support patients and healthcare providers to make a decision about whether to discontinue BZD/BRZA hypnotics.
描述一种用于慢性失眠的决策辅助工具(DA)的开发和可接受性,该工具考虑了苯二氮䓬类(BZD)和苯二氮䓬受体激动剂(BZRA)催眠药物的停药问题,如果停药,是否需要逐渐减少剂量,同时或不进行失眠认知行为疗法(CBT-I)。
我们回顾了描述慢性失眠的相关文献,以确定各种选择。我们使用之前进行的系统评价和荟萃分析的结果,来确定两种选择的相关结果:单独逐渐减少 BZD/BZRA 催眠药物的剂量和逐渐减少 BZD/BZRA 催眠药物并同时进行 CBT-I。然后,我们按照国际患者决策辅助工具标准制定了 DA 的原型。我们进行了一项混合方法调查,以评估患者和医疗保健提供者对其的可接受性。
原型包括对失眠的描述、继续或停止使用 BZD/BRZA 催眠药物的选择(如果停止使用,逐渐减少催眠药物剂量并同时或不进行 CBT-I 的选择)、每个选择的优缺点,以及一个价值澄清练习。患者(n=24)报告称,DA 的语言表达(79%)、信息量(71%)和呈现方式(91%)都具有可接受性。医疗保健提供者(n=20)也提供了积极的反馈。
我们为考虑停止使用 BZD/BRZA 催眠药物的慢性失眠患者开发了一种 DA,该 DA 得到了利益相关者的认可。所开发的 DA 旨在支持患者和医疗保健提供者做出是否停止使用 BZD/BRZA 催眠药物的决策。