Division of Endocrinology, Boston Children's Hospital, Boston, Massachusetts, USA.
Clinical Research Operations Center, Boston Children's Hospital, Boston, Massachusetts, USA.
J Nurs Scholarsh. 2022 Jan;54(1):104-116. doi: 10.1111/jnu.12704. Epub 2021 Nov 22.
To review the extant literature relevant to perceptions by direct care nurses toward clinical research endeavors.
An integrative review guided by the socioecological model was conducted.
Five databases were searched to identify relevant peer-reviewed articles; there was no limitation on publication date.
The final sample (N = 9) was systematically appraised. Numerous barriers to direct care nurses' ability to perform study activities on clinical research trials were encountered at all levels: (1) personal-comprehension, education, and training; (2) interpersonal-communication issues within or from the study team, failure to advocate for the patient; (3) organizational-lack of leadership support, knowledge, and time; and (4) community-insufficient guidance and oversight by research-governing bodies.
Direct care nurses report numerous barriers to completing protocol-administered activities for their patients participating in clinical research. A dearth of robust research exists in describing the reasons for, or persistence of, barriers faced by direct care nurses to assisting with research, and there have been little to no interventions to address them.
As translational research evolves and becomes more complex, there is the need to ensure both the care of clinical research participants and the integrity of the research. Direct care nurses are critical to this endeavor, and potential barriers they face may have significant ramifications for the research enterprise. Recognition of these barriers and eventual interventions designed to address them are needed.
回顾直接护理护士对临床研究工作的看法的相关文献。
采用社会生态学模式指导的综合回顾。
在五个数据库中搜索相关的同行评审文章；对发表日期没有限制。
对最终样本（N=9）进行了系统评估。直接护理护士在各个层面上进行临床试验研究活动的能力都遇到了许多障碍：（1）个人——理解、教育和培训；（2）来自或来自研究团队的人际沟通问题，未能为患者辩护；（3）组织——缺乏领导力支持、知识和时间；以及（4）社区——研究监管机构提供的指导和监督不足。
直接护理护士报告说，他们在为参与临床研究的患者完成协议管理活动方面遇到了许多障碍。关于直接护理护士在协助研究方面面临障碍的原因或持续存在的原因，缺乏强有力的研究描述，并且几乎没有干预措施来解决这些障碍。
随着转化研究的发展和变得更加复杂，需要确保临床研究参与者的护理和研究的完整性。直接护理护士对此项工作至关重要，他们面临的潜在障碍可能对研究事业产生重大影响。需要认识到这些障碍，并最终设计干预措施来解决这些障碍。
