Jia Sharon, Luong Thuyvi
WellSpan York Hospital, Department of Emergency Medicine, York, Pennsylvania.
Clin Pract Cases Emerg Med. 2021 Nov;5(4):440-442. doi: 10.5811/cpcem.2021.7.53596.
Varicella zoster virus (VZV) meningitis is primarily an infection of the immuno-compromised. However, it can also affect immunocompetent individuals. Reactivation of VZV typically presents with a distinct dermatomal rash suggestive of varicella zoster, but there have also been reports of VZV meningitis presenting without a rash.
We describe a case of VZV meningitis in a healthy, 30-year-old male presenting to the emergency department shortly after receiving his first coronavirus disease 2019 vaccination. He was treated with intravenous acyclovir and then discharged home on oral valacyclovir.
Emergency physicians should consider aseptic meningitis in immunocompetent patients presenting with atypical headaches in this population.
水痘带状疱疹病毒(VZV)脑膜炎主要发生于免疫功能低下者。然而,它也可影响免疫功能正常的个体。VZV再激活通常表现为具有水痘带状疱疹特征的明显皮节皮疹,但也有VZV脑膜炎无皮疹的报道。
我们描述了一例30岁健康男性在接种第一剂2019冠状病毒病疫苗后不久到急诊科就诊,被诊断为VZV脑膜炎的病例。他接受了静脉注射阿昔洛韦治疗,随后口服伐昔洛韦出院。
对于该人群中出现非典型头痛的免疫功能正常患者,急诊医生应考虑无菌性脑膜炎的可能。