Acta Chir Plast. 2021 Fall;63(3):118-126. doi: 10.48095/ccachp2021118.
Postoperative facial scars after plastic and reconstructive surgery are visible results that can seriously affect the quality of life of recovering patients. Currently, platelet-rich plasma (PRP) is widely used in medicine to improve tissue regeneration.
To analyze the esthetic outcomes of using PRP in the late postoperative period of maxillofacial surgical interventions.
A total of 100 patients aged 18-60 years who were undergoing plastic and reconstructive surgery in the maxillofacial region were included in this study. The patients were randomly divided in two groups. Fifty patients in the treatment group received PRP injections at the time of surgery. Patients in the control group did not receive any injections. PRP was injected intradermally after suturing the wound. Evaluation of treatment outcomes was carried out by planimetry, the Image J programme during 1 month after surgery and by the Patient and Observer Scar Assessment Scale 30 and 90 days after the surgical procedure. The Dermatological Quality of Life Index was used to assess the negative impact of treatment outcomes on various aspects of the patients life.
The change of scar width was twice less pronounced in the treatment group. The patients in the treatment group were more satisfied with the results of the treatment and had a higher quality of life. The treatment group exhibited less scaring at all time points than the control group 3 months after surgery.
The use of PRP had a pronounced beneficial therapeutic effect in influencing the esthetic outcomes of surgical interventions.
整形和重建手术后的面部疤痕是可见的结果，会严重影响恢复患者的生活质量。目前，富血小板血浆（PRP）在医学中被广泛用于改善组织再生。
分析 PRP 在颌面外科干预术后晚期的美容效果。
本研究纳入了 100 名 18-60 岁接受颌面整形和重建手术的患者。患者随机分为两组。治疗组 50 名患者在手术时接受 PRP 注射。对照组患者未接受任何注射。在缝合伤口后，将 PRP 皮内注射。术后 1 个月通过皮尺、Image J 程序，以及术后 30 天和 90 天的患者和观察者疤痕评估量表（Patient and Observer Scar Assessment Scale）评估治疗效果。使用皮肤病生活质量指数（Dermatological Quality of Life Index）评估治疗结果对患者生活各个方面的负面影响。
治疗组的疤痕宽度变化明显较小。治疗组患者对治疗结果更满意，生活质量更高。与对照组相比，治疗组在术后 3 个月时的疤痕明显更少。
PRP 的使用对手术干预的美容效果具有显著的有益治疗作用。
