Guangdong Civil Servant Health Examination Center, Guangdong Provincial People's Hospital, Guangzhou, China.
Guangdong Academy of Medical Sciences, Guangzhou, China.
J Int Med Res. 2021 Nov;49(11):3000605211053754. doi: 10.1177/03000605211053754.
Resting heart rate (RHR) independently predicts cardiovascular death. Increased RHR is related to chronic diseases, but community-based studies are rare. We investigated this population and factors related to RHR.
In total, 374 participants underwent medical examinations from March 2019 to December 2019. Participants were divided into groups with low RHR (LRHR; <65 beats/minute) and high RHR (HRHR; ≥65 beats/minute). RHR was judged using resting electrocardiogram at physical examination. We conducted laboratory examinations, including glycosylated hemoglobin (HbA1c), fasting plasma glucose (FPG), and blood lipids, among participants with chronic diseases. We used Cox proportional risk regression and multivariate analyses for the following covariates: previous chronic diseases, body mass index (BMI), smoking, blood lipids, and FPG.
The incidence of type 2 diabetes mellitus (T2DM) and HbA1c values were both significantly higher in the HRHR group than in the LRHR group. Spearman correlation analysis showed RHR had a positive correlation with low-density lipoprotein, BMI, FPG, and HbA1c (r = 0.104574, 0.117266, 0.116041, and 0.311761, respectively). Multiple linear regression analysis showed age, hypertension, T2DM, and HbA1c were factors influencing RHR.
RHR showed strong correlation with T2DM and HbA1c in our community population, suggesting that RHR may be a risk factor for cardiovascular disease.
静息心率（RHR）可独立预测心血管死亡。RHR 升高与慢性病有关，但基于社区的研究较少。我们调查了该人群及与 RHR 相关的因素。
共有 374 名参与者于 2019 年 3 月至 2019 年 12 月接受了体检。参与者被分为低 RHR（LRHR；<65 次/分钟）和高 RHR（HRHR；≥65 次/分钟）组。RHR 通过体检时的静息心电图判断。我们对患有慢性病的参与者进行了实验室检查，包括糖化血红蛋白（HbA1c）、空腹血糖（FPG）和血脂。我们使用 Cox 比例风险回归和多变量分析以下协变量：既往慢性病、体重指数（BMI）、吸烟、血脂和 FPG。
HRHR 组的 2 型糖尿病（T2DM）发生率和 HbA1c 值均显著高于 LRHR 组。Spearman 相关分析显示 RHR 与低密度脂蛋白、BMI、FPG 和 HbA1c 呈正相关（r=0.104574、0.117266、0.116041 和 0.311761）。多元线性回归分析显示，年龄、高血压、T2DM 和 HbA1c 是影响 RHR 的因素。
在我们的社区人群中，RHR 与 T2DM 和 HbA1c 密切相关，提示 RHR 可能是心血管疾病的危险因素。
