头孢美唑对厌氧菌的活性。
Activity of cefmetazole against anaerobic bacteria.
作者信息
Cornick N A, Jacobus N V, Gorbach S L
机构信息
Department of Community Health, Tufts University School of Medicine, Boston, Massachusetts.
出版信息
Antimicrob Agents Chemother. 1987 Dec;31(12):2010-2. doi: 10.1128/AAC.31.12.2010.
Abstract
The in vitro activity of cefmetazole versus that of other antimicrobial drugs was assessed against 374 clinical isolates of Bacteroides spp., Clostridium spp., and anaerobic gram-positive cocci. Compared with cefoxitin, cefmetazole showed good activity against Bacteroides fragilis, other Bacteroides species, and anaerobic cocci. It was somewhat less active than cefoxitin against Bacteroides thetaiotaomicron, B. ovatus, B. distasonis, and B. vulgatus and somewhat more active against Clostridium spp.
摘要
针对374株拟杆菌属、梭菌属和厌氧革兰氏阳性球菌的临床分离株，评估了头孢美唑与其他抗菌药物的体外活性。与头孢西丁相比，头孢美唑对脆弱拟杆菌、其他拟杆菌属菌种以及厌氧球菌显示出良好的活性。它对多形拟杆菌、卵形拟杆菌、解脲拟杆菌和普通拟杆菌的活性略低于头孢西丁，而对梭菌属的活性略高。
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