School of psychology and mental health, North China University of Science and Technology, Tangshan, China.
The National Clinical Research Center for Mental Disorders & Beijing Key Laboratory of Mental Disorders Beijing Anding Hospital & the Advanced Innovation Center for Human Brain Protection, Capital Medical University, School of Mental Health, Beijing, China.
Early Interv Psychiatry. 2022 Oct;16(10):1112-1120. doi: 10.1111/eip.13259. Epub 2021 Nov 23.
The present study aimed to investigate the prevalence rate of objective and subjective psychosis-like experiences (PLEs) in non-help-seeking college students and to explore their differential contributions to suicidal ideation.
First-year college students were recruited and surveyed with the Chinese version of the 16-item Prodromal Questionnaire (CPQ-16), Childhood Trauma Questionnaire (CTQ-SF), Patient Health Questionnaire-9 (PHQ-9), General Anxiety Disorder-7 (GAD-7) and Beck Scale for Suicide Ideation (BSI). The Structured Interview of Psychosis-Risk Syndromes (SIPS) was conducted in individuals with a CPQ-16 score of 9 or higher.
Data were available for 8367 students. Three hundred and seventy of them scored 9 or higher on the CPQ-16, suggesting potential PLEs (4.42%). Among them, 194 agreed to the SIPS screening. The PLEs were confirmed in 103 individuals who scored 1-5 on any positive symptom scales of the SIPS (objective PLEs, oPLEs). For the remaining 91 individuals, their PLEs were not confirmed by the SIPS and thus were categorized as individuals with subjective PLEs (sPLEs). In univariate logistic regression, oPLEs was associated with a two times risk of suicidal ideation compared to sPLEs (OR = 1.971, p = .029). In multivariate logistic regression when non-PLE status was set as a reference, oPLEs significantly predicted suicidal ideation (OR = 3.441, p = .011), while the sPLEs (OR = 2.277, p = .091) was no longer a significant predictor after controlling for PHQ-9, GAD-7 and CPQ-SF scores.
OPLEs and sPLEs have differential contributions to suicidal ideation. OPLEs seems to be associated with a higher risk of suicidal ideation and is independent of other psychopathology.
本研究旨在调查非求助大学生中客观和主观精神病样体验(PLEs)的患病率,并探讨其对自杀意念的不同贡献。
招募了一年级大学生,并使用中文版 16 项前驱症状问卷(CPQ-16)、儿童创伤问卷(CTQ-SF)、患者健康问卷-9(PHQ-9)、广泛性焦虑障碍-7(GAD-7)和贝克自杀意念量表(BSI)进行调查。在 CPQ-16 得分 9 或更高的个体中进行结构访谈精神病风险综合征(SIPS)。
共有 8367 名学生的数据可用。其中 370 名学生 CPQ-16 得分 9 或更高,提示存在潜在的 PLE(4.42%)。其中,194 名同意接受 SIPS 筛查。SIPS 任何阳性症状量表评分 1-5 的 103 人 PLE 得到确认(客观 PLE,oPLE)。对于其余 91 人,SIPS 未确认其 PLE,因此归类为具有主观 PLE(sPLE)的个体。在单变量逻辑回归中,oPLE 与自杀意念的风险增加两倍相关,与 sPLE 相比(OR=1.971,p=0.029)。在多元逻辑回归中,当非 PLE 状态作为参考时,oPLE 显著预测自杀意念(OR=3.441,p=0.011),而 sPLE(OR=2.277,p=0.091)在控制 PHQ-9、GAD-7 和 CPQ-SF 评分后不再是显著预测因子。
oPLE 和 sPLE 对自杀意念有不同的贡献。oPLE 似乎与自杀意念的风险增加有关,且独立于其他精神病理学。