Kim Sung-Wan, Chung Young-Chul, Kang Young-Shin, Kim Jae-Kyeong, Jang Ji-Eun, Jhon Min, Lee Ju-Yeon, Kim Jae-Min, Shin Il-Seon, Yoon Jin-Sang
Mindlink, Gwangju Bukgu Community Mental Health Center, Gwangju, Republic of Korea.
Department of Psychiatry, Chonnam National University Medical School, Gwangju, Republic of Korea.
Psychiatry Investig. 2018 Feb;15(2):111-117. doi: 10.30773/pi.2017.04.24. Epub 2017 Nov 29.
To examine the reliability and validity of the Korean version of the 16-item Prodromal Questionnaire (KPQ-16) in non-help-seeking university students.
Among 2,246 university students participated in the initial screening, 257 subjects with KPQ-16 scores ≥4 were interviewed. The criteria for ultra-high risk (UHR) of psychosis of the Comprehensive Assessment of At-Risk Mental States (CAARMS) were the gold standard for diagnosis. An exploratory modified version of the questionnaire (mKPQ-16), to which three items from the Eppendorf Schizophrenia Inventory were added, was also used to compensate for items on thought and cognitive problems.
Seventeen subjects met the CAARMS criteria for UHR of psychosis. The area under the receiver operating characteristic curve (AUROC) was highest for the mKPQ-16 total score (AUROC=0.831, p<0.001). The use of cutoff total scores of 7 for the mKPQ-16 and 6 for the KPQ-16 resulted in the best balance of sensitivity (76.5% and 64.7%, respectively) and specificity (75.4% and 71.2%, respectively).
The Korean versions of the PQ-16 are good instruments for screening for psychosis risk in university students. This validation of a questionnaire version with a small number of items may make it feasible to screen large numbers of young adults in the community.
检验16项前驱症状问卷韩语版（KPQ - 16）在未寻求帮助的大学生中的信度和效度。
在参与初始筛查的2246名大学生中，对257名KPQ - 16得分≥4的受试者进行访谈。高危精神状态综合评估（CAARMS）的精神病超高危（UHR）标准是诊断的金标准。还使用了问卷的探索性修订版（mKPQ - 16），其中添加了来自埃彭多夫精神分裂症量表的三个项目，以补充关于思维和认知问题的项目。
17名受试者符合CAARMS的精神病UHR标准。mKPQ - 16总分的受试者工作特征曲线下面积（AUROC）最高（AUROC = 0.831，p < 0.001）。mKPQ - 16总分临界值设为7，KPQ - 16总分临界值设为6时，敏感性（分别为76.5%和64.7%）和特异性（分别为75.4%和71.2%）达到最佳平衡。
PQ - 16韩语版是筛查大学生精神病风险的良好工具。这种少量项目问卷版本的验证可能使在社区中筛查大量年轻人成为可行。
