University of Hawaii Cancer Center, Honolulu, Hawaii.
University of Hawaii Cancer Center, 701 Ilalo St, Honolulu, HI 96813. Email:
Prev Chronic Dis. 2021 Nov 24;18:E98. doi: 10.5888/pcd18.210240.
Several Asian racial and ethnic groups, including individuals of Filipino ancestry, are at higher risk of developing type 2 diabetes than White individuals, despite their lower body mass index (BMI). This study examined determinants of type 2 diabetes among Filipino American adults in the Multiethnic Cohort Study.
Participants in Hawaii and Los Angeles completed questionnaires on demographics, diet, and anthropometrics. Generational status was determined according to birthplace of participants and their parents. Based on self-reported data and data on medications, type 2 diabetes status was classified as no, prevalent, or incident. We used polytomous logistic regression, while adjusting for confounders, to obtain odds ratios.
Among 10,681 Multiethnic Cohort Study participants reporting any Filipino ancestry, 57% were 1st-, 17% were 2nd-, and 25% were 3rd-generation Filipino Americans. Overall, 13% and 17% of participants had a prevalent or incident type 2 diabetes diagnosis. Overweight and obesity and the presence of other risk factors increased from the 1st to subsequent generations. First-generation immigrants were less likely to report type 2 diabetes at cohort entry than immigrants of subsequent generations who were born in the US or whose parents were born in the US; only the prevalence of type 2 diabetes was significantly elevated in the 2nd generation compared with the 1st generation.
The results support the hypothesis that Filipino migrants adopt lifestyle factors of the host country and subsequent generations experience higher type 2 diabetes rates due to changes in risk factor patterns.
包括菲律宾裔在内的一些亚洲种族和民族群体,尽管体重指数(BMI)较低,但患 2 型糖尿病的风险高于白人。本研究在夏威夷和洛杉矶的菲律宾裔美国成年人中检查了 2 型糖尿病的决定因素。
参与者完成了关于人口统计学、饮食和人体测量学的问卷。根据参与者及其父母的出生地确定代际地位。根据自我报告的数据和药物数据,将 2 型糖尿病的状态分为无、现患或新发。我们使用多分类逻辑回归,同时调整混杂因素,得出优势比。
在报告有任何菲律宾血统的 10681 名多民族队列研究参与者中,57%是第一代,17%是第二代,25%是第三代菲律宾裔美国人。总体而言,13%和 17%的参与者患有现患或新发 2 型糖尿病。超重和肥胖以及其他危险因素的存在从第一代增加到后续几代。第一代移民在队列入组时报告 2 型糖尿病的可能性低于在美国出生或父母在美国出生的后续几代移民;只有第二代的 2 型糖尿病患病率明显高于第一代。
结果支持这样一种假设,即菲律宾移民采用了东道国的生活方式因素,而随后几代人由于危险因素模式的变化,患 2 型糖尿病的风险更高。