Al-Qahtani Mohammad H, AlQahtani Fai A
Department of Pediatrics, Collage of Medicine, King Fahad Hospital of the University, Imam Abdulrahman Bin Faisal University, Alkhobar, Saudi Arabia.
Case Rep Med. 2021 Nov 15;2021:6397338. doi: 10.1155/2021/6397338. eCollection 2021.
Chronic uncontrolled type 1 diabetes mellitus (type 1DM) is a very major risk for chronic systemic complications; specifically, the microvascular and macrovascular ones. Limited joint mobility (LJM) is a rare disease that complicates all types of diabetes and might indicate the high-risk odd for the diabetic patients to develop microvascular complications. We are reporting a 13-year-old female child with chronic uncontrolled type 1DM presenting with full blown clinical picture of bilateral hand LJM associated with significant growth failure yet has no clinical or biochemical evidence of microvascular complications. Literature research studies have emphasized the rarity of this manifestation in pediatric type 1 diabetic patients; however, it is an important clue and warning sign for microvascular complication occurrence in these patients.
慢性未控制的1型糖尿病（1型糖尿病）是慢性全身性并发症的一个非常主要的风险因素；具体而言，是微血管和大血管并发症。关节活动受限（LJM）是一种罕见疾病，会使所有类型的糖尿病复杂化，可能预示糖尿病患者发生微血管并发症的高风险几率。我们报告一名13岁女性儿童，患有慢性未控制的1型糖尿病，出现双侧手部LJM的典型临床表现，并伴有明显生长发育迟缓，但尚无微血管并发症的临床或生化证据。文献研究强调了这种表现在儿童1型糖尿病患者中的罕见性；然而，它是这些患者发生微血管并发症的一个重要线索和警示信号。
