Dong Wen-Lan, An Jing, Yu Miao, Yin Peng, Xu Ting-Ling, Liu Bo, Zuberbier Torsten, Zhao Zuo-Tao, Zhou Mai-Geng
National Center for Chronic and Noncommunicable Disease Control and Prevention, Beijing 100050, People's Republic of China.
Beijing Xicheng District Maternal and Child Health Hospital, Beijing 100054, People's Republic of China.
World Allergy Organ J. 2021 Nov 9;14(11):100604. doi: 10.1016/j.waojou.2021.100604. eCollection 2021 Nov.
Atopic dermatitis (AD) is a chronic disease with growing prevalence and has become a global public health problem. However, little is known about the burden caused by AD in China.
To access the prevalence and burden of AD in China.
We estimated the prevalence and year lived with disability (YLD) of AD in China, by different age and sex groups. We also compared the burden of AD in China with other countries in the Group of Twenty (G20). We analyzed the changes in the number of AD patients and their YLDs by cause decomposition from 1990 to 2019.
AD was the twenty-fourth leading cause of the burden of 369 diseases in China in 2019. From 1990 to 2019, the age-standardized prevalence and YLD rate of AD in China increased by 1.04% and 1.43% respectively, which were the second and the largest increase among the G20 and both higher than the global average (-4.29% and -4.14%). The number of patients with AD increased by 25.65%, of which 20.16% was due to population growth, 3.85% due to population aging, and 1.64% due to age-specific prevalence. Both the prevalence and YLD rate of AD were higher in 1 to 4 year-olds and 95+ years age group. Before the age of 10, the prevalence and YLD rate of AD in males were higher than those in females, while there was a marked sex shift at the ages of 10 to 14.
AD is a serious public health problem in China. Substantial variations exist in burden due to AD between male and female, and in age groups. Considering these findings will be important for developing preventive strategies and treatments to reduce the burden of AD.
特应性皮炎（AD）是一种患病率不断上升的慢性疾病，已成为一个全球性的公共卫生问题。然而，在中国，关于AD所造成的负担知之甚少。
评估中国AD的患病率和负担。
我们按不同年龄和性别组估计了中国AD的患病率和失能生存年数（YLD）。我们还将中国AD的负担与二十国集团（G20）中的其他国家进行了比较。我们通过病因分解分析了1990年至2019年AD患者数量及其YLD的变化。
2019年，AD在中国369种疾病负担中位列第24位。1990年至2019年，中国AD的年龄标准化患病率和YLD率分别上升了1.04%和1.43%，在G20中分别位列第二和第一，均高于全球平均水平（-4.29%和-4.14%）。AD患者数量增加了25.65%，其中20.16%归因于人口增长，3.85%归因于人口老龄化，1.64%归因于特定年龄组的患病率。1至4岁年龄组和95岁及以上年龄组的AD患病率和YLD率均较高。10岁之前，男性AD的患病率和YLD率高于女性，而在10至14岁时出现了明显的性别转变。
AD在中国是一个严重的公共卫生问题。AD造成的负担在男性和女性以及不同年龄组之间存在显著差异。考虑到这些发现对于制定预防策略和治疗方法以减轻AD负担至关重要。
