Homi J, Notcutt W, Jones J J, Sparke B R
Br J Anaesth. 1978 May;50(5):435-44. doi: 10.1093/bja/50.5.435.
Damage to the trachea produced in dogs by large and small residual volume cuffs during 6 h of IPPV was compared using a specially designed endotracheal tube. The cuffs under evaluation were adjusted to exert similar average pressures on the tracheal wall, so that many of the variables believed responsible for tracheal injury were controlled. The true compliance of the cuff was measured with the tube inside and outside the trachea of the anaesthetized dogs. The maximum estimated pressure transmitted to the tracheal wall, derived from these compliance curves, was found to equal the peak airway pressure in the presence of a small air leak past each cuff. At various tracheal wall pressures there were only very minor differences in tracheal damage between the large and small residual volume cuffs tested.
使用一种特殊设计的气管内导管，比较了在间歇正压通气6小时期间，大残余容积袖带和小残余容积袖带对犬气管造成的损伤。所评估的袖带被调整为对气管壁施加相似的平均压力，以便控制许多被认为是造成气管损伤的变量。在麻醉犬的气管内外，用该导管测量袖带的真实顺应性。从这些顺应性曲线得出的传递到气管壁的最大估计压力，发现在每个袖带存在小漏气的情况下等于气道峰值压力。在不同的气管壁压力下，所测试的大残余容积袖带和小残余容积袖带之间的气管损伤只有非常微小的差异。
