Institution: Health Management Center, The Third Xiangya Hospital of Central South University, China.
Institution: Xiangya Nursing School, Central South University, Changsha, China.
J Affect Disord. 2022 Feb 15;299:60-66. doi: 10.1016/j.jad.2021.11.054. Epub 2021 Nov 23.
The purpose of this study was to screen for depressive symptoms in a large sample of Chinese population, and explore the effects of demographic and lifestyle factors on depressive symptoms based on the brain maturity.
Adults from 8 health management centers in 6 provinces completed an online health self-report questionnaire. Finally, a total of 76,223 valid questionnaires were collected.
A total of 76,223 participants were included in this study, including 44,167 (57.9%) males and 32,056 (42.1%) females. The percentage of clinically relevant depressive symptoms among young, early mature and late mature participants was 13.5%, 18.5% and 27.3%, respectively. Among young participants, being female was a risk factor for depressive symptoms, while having a bachelor's or graduate degree, being married, smoking, and moderate alcohol consumption were protective factors. And among early mature participants, female, married and other marital status, BMI of 24-27.9 were risk factors, post-graduate education or above, smoking, moderate alcohol consumption and meeting exercise standard were protective factors. Among late mature participants, Compared with junior high school, all other degrees were protective factors, as was meeting physical activity standards, excessive alcohol consumption was a risk factor.
This study analyzed the association among young, early mature and late mature participants respectively, and proposed strategies for improving healthy lifestyle of Chinese people. Our findings support the need for individualized recommendations to improve mental health based on brain maturity.
本研究旨在对大量中国人群进行抑郁症状筛查,并根据大脑成熟度探讨人口统计学和生活方式因素对抑郁症状的影响。
来自 6 个省的 8 个健康管理中心的成年人完成了在线健康自我报告问卷。最终共收集到 76223 份有效问卷。
本研究共纳入 76223 名参与者,其中 44167 名(57.9%)为男性,32056 名(42.1%)为女性。青年、早期成熟和晚期成熟参与者中出现临床相关抑郁症状的比例分别为 13.5%、18.5%和 27.3%。在青年参与者中,女性是抑郁症状的危险因素,而拥有本科或研究生学历、已婚、吸烟和适度饮酒是保护因素。在早期成熟的参与者中,女性、已婚和其他婚姻状况、BMI 为 24-27.9 是危险因素,研究生及以上学历、吸烟、适度饮酒和符合运动标准是保护因素。在晚期成熟的参与者中,与初中相比,其他所有学历均为保护因素,符合身体活动标准、过量饮酒为危险因素。
本研究分别分析了青年、早期成熟和晚期成熟参与者之间的关联,并提出了改善中国人健康生活方式的策略。我们的研究结果支持了根据大脑成熟度为改善心理健康提供个性化建议的必要性。