Department of Orthopedic Surgery, Chonnam National University Medical School and Hospital, 322 Seoyang-ro, Hwasun-eup, Hwasun-gun, Jeollanam-do, Republic of Korea.
College of Natural Science, School of Statistics, University of Seoul, Seoul, Republic of Korea.
BMC Musculoskelet Disord. 2022 Feb 8;23(1):127. doi: 10.1186/s12891-022-05080-8.
Both high tibial osteotomy (HTO) and unicompartmental knee arthroplasty (UKA) are well-established treatments for medial knee osteoarthritis (OA). However, over the past 20 years, results of comparisons of long-term survival rates and outcomes have remained controversial. Furthermore, in patients at the boundary age, from 50 to 70 years, considering age as a treatment indication, selecting a surgical method is difficult. Therefore, we aimed to investigate conversion rates to total knee arthroplasty (TKA) and perioperative adverse outcomes between the two surgical methods in mid-age patients.
We extracted data from the Korean National Health Insurance claims database. A total of 70,464 patients aged between 50 and 70 years, considered as mid-age patients were included in the final study population. We used a multivariable Cox proportional hazard regression model, adjusting for potential confounders such as age, sex, insurance type, region of residence, hospital type, comorbidities, and the Charlson comorbidity Index (CCI).
Of the 70,464 patients, 21,194 were treated with UKA and 49,270 were treated with HTO. HTO showed a higher risk of revision than UKA at five, and 10 years and during the whole observation period. The incidence of deep vein thromboembolism, and surgical site infection was significantly higher in UKA than in HTO.
It is important to choose an appropriate surgical method considering that UKA has better results in terms of long-term survival rates but may have a higher incidence of various complications.
高位胫骨截骨术(HTO)和单髁膝关节置换术(UKA)都是治疗内侧膝关节骨关节炎(OA)的成熟方法。然而,在过去的 20 年中,关于两种方法的长期生存率和结果的比较一直存在争议。此外,在 50 至 70 岁的年龄边界患者中,考虑到年龄作为治疗指征,选择手术方法比较困难。因此,我们旨在研究两种手术方法在中年患者中的翻修率和围手术期不良结局。
我们从韩国国家健康保险索赔数据库中提取数据。最终研究人群包括年龄在 50 至 70 岁之间的 70464 名患者。我们使用多变量 Cox 比例风险回归模型,调整了年龄、性别、保险类型、居住地、医院类型、合并症和 Charlson 合并症指数(CCI)等潜在混杂因素。
在 70464 名患者中,21194 名患者接受 UKA 治疗,49270 名患者接受 HTO 治疗。HTO 在 5 年和 10 年以及整个观察期内的翻修风险均高于 UKA。UKA 比 HTO 更易发生深静脉血栓形成和手术部位感染等并发症。
考虑到 UKA 在长期生存率方面的结果更好,但可能会有更高的各种并发症发生率,因此选择合适的手术方法非常重要。