• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

一项来自韩国国家索赔数据的针对中年患者的 21194 例 UKA 和 49270 例 HTO 手术的意外事件风险的比较研究。

A comparative study of 21,194 UKAs and 49,270 HTOs for the risk of unanticipated events in mid-age patients from the national claims data in South Korea.

机构信息

Department of Orthopedic Surgery, Chonnam National University Medical School and Hospital, 322 Seoyang-ro, Hwasun-eup, Hwasun-gun, Jeollanam-do, Republic of Korea.

College of Natural Science, School of Statistics, University of Seoul, Seoul, Republic of Korea.

出版信息

BMC Musculoskelet Disord. 2022 Feb 8;23(1):127. doi: 10.1186/s12891-022-05080-8.

DOI:10.1186/s12891-022-05080-8
PMID:35135508
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8827168/
Abstract

BACKGROUND

Both high tibial osteotomy (HTO) and unicompartmental knee arthroplasty (UKA) are well-established treatments for medial knee osteoarthritis (OA). However, over the past 20 years, results of comparisons of long-term survival rates and outcomes have remained controversial. Furthermore, in patients at the boundary age, from 50 to 70 years, considering age as a treatment indication, selecting a surgical method is difficult. Therefore, we aimed to investigate conversion rates to total knee arthroplasty (TKA) and perioperative adverse outcomes between the two surgical methods in mid-age patients.

METHODS

We extracted data from the Korean National Health Insurance claims database. A total of 70,464 patients aged between 50 and 70 years, considered as mid-age patients were included in the final study population. We used a multivariable Cox proportional hazard regression model, adjusting for potential confounders such as age, sex, insurance type, region of residence, hospital type, comorbidities, and the Charlson comorbidity Index (CCI).

RESULTS

Of the 70,464 patients, 21,194 were treated with UKA and 49,270 were treated with HTO. HTO showed a higher risk of revision than UKA at five, and 10 years and during the whole observation period. The incidence of deep vein thromboembolism, and surgical site infection was significantly higher in UKA than in HTO.

CONCLUSIONS

It is important to choose an appropriate surgical method considering that UKA has better results in terms of long-term survival rates but may have a higher incidence of various complications.

摘要

背景

高位胫骨截骨术(HTO)和单髁膝关节置换术(UKA)都是治疗内侧膝关节骨关节炎(OA)的成熟方法。然而,在过去的 20 年中,关于两种方法的长期生存率和结果的比较一直存在争议。此外,在 50 至 70 岁的年龄边界患者中,考虑到年龄作为治疗指征,选择手术方法比较困难。因此,我们旨在研究两种手术方法在中年患者中的翻修率和围手术期不良结局。

方法

我们从韩国国家健康保险索赔数据库中提取数据。最终研究人群包括年龄在 50 至 70 岁之间的 70464 名患者。我们使用多变量 Cox 比例风险回归模型,调整了年龄、性别、保险类型、居住地、医院类型、合并症和 Charlson 合并症指数(CCI)等潜在混杂因素。

结果

在 70464 名患者中,21194 名患者接受 UKA 治疗,49270 名患者接受 HTO 治疗。HTO 在 5 年和 10 年以及整个观察期内的翻修风险均高于 UKA。UKA 比 HTO 更易发生深静脉血栓形成和手术部位感染等并发症。

结论

考虑到 UKA 在长期生存率方面的结果更好,但可能会有更高的各种并发症发生率,因此选择合适的手术方法非常重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/effb/8827168/705d9ee07ef1/12891_2022_5080_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/effb/8827168/9c74181234be/12891_2022_5080_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/effb/8827168/705d9ee07ef1/12891_2022_5080_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/effb/8827168/9c74181234be/12891_2022_5080_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/effb/8827168/705d9ee07ef1/12891_2022_5080_Fig2_HTML.jpg

相似文献

1
A comparative study of 21,194 UKAs and 49,270 HTOs for the risk of unanticipated events in mid-age patients from the national claims data in South Korea.一项来自韩国国家索赔数据的针对中年患者的 21194 例 UKA 和 49270 例 HTO 手术的意外事件风险的比较研究。
BMC Musculoskelet Disord. 2022 Feb 8;23(1):127. doi: 10.1186/s12891-022-05080-8.
2
Management of medial femorotibial osteoarthritis: Epidemiology, and survival of unicompartmental knee arthroplasty versus valgus high tibial osteotomy in France. Study of 108,007 cases from the French National Hospitals Database.中文译文:法国膝关节单髁置换术与外侧胫骨高位截骨术治疗内侧股胫关节骨关节炎的管理:一项基于法国国家医院数据库的 108007 例病例的研究。流行病学及生存率比较。
Orthop Traumatol Surg Res. 2023 Dec;109(8):103692. doi: 10.1016/j.otsr.2023.103692. Epub 2023 Sep 28.
3
Unicompartmental Knee Arthroplasty Has Lower Infection, Conversion, and Complication Rates Compared to High Tibial Osteotomy.单髁膝关节置换术感染率、翻修率和并发症发生率均低于高胫骨截骨术。
J Knee Surg. 2022 Dec;35(14):1518-1523. doi: 10.1055/s-0042-1757597. Epub 2022 Dec 20.
4
Reduced survival of total knee arthroplasty after previous unicompartmental knee arthroplasty compared with previous high tibial osteotomy: a propensity-score weighted mid-term cohort study based on 2,133 observations from the Danish Knee Arthroplasty Registry.与先前的胫骨高位截骨术相比,先前的单髁膝关节置换术后全膝关节置换术的生存率降低:基于丹麦膝关节置换登记处的 2133 例观察的倾向评分加权中期队列研究。
Acta Orthop. 2020 Apr;91(2):177-183. doi: 10.1080/17453674.2019.1709711. Epub 2020 Jan 13.
5
Long-term survival is similar between closed-wedge high tibial osteotomy and unicompartmental knee arthroplasty in patients with similar demographics.在具有相似人口统计学特征的患者中,闭合楔形胫骨高位截骨术与单髁膝关节置换术的长期存活率相似。
Knee Surg Sports Traumatol Arthrosc. 2019 Apr;27(4):1310-1319. doi: 10.1007/s00167-019-05390-w. Epub 2019 Feb 4.
6
The impact of a high tibial valgus osteotomy and unicondylar medial arthroplasty on the treatment for knee osteoarthritis: a meta-analysis.高胫骨外翻截骨术和单髁内侧关节成形术治疗膝骨关节炎的影响:一项荟萃分析。
Knee Surg Sports Traumatol Arthrosc. 2013 Jan;21(1):96-112. doi: 10.1007/s00167-011-1751-2. Epub 2011 Nov 11.
7
Higher survival rate in total knee arthroplasty after high tibial osteotomy than that after unicompartmental knee arthroplasty.高位胫骨截骨术后全膝关节置换术的生存率高于单髁膝关节置换术后的生存率。
Knee Surg Sports Traumatol Arthrosc. 2023 Mar;31(3):1132-1142. doi: 10.1007/s00167-021-06641-5. Epub 2021 Jun 24.
8
Older age increases the risk of revision and perioperative complications after high tibial osteotomy for unicompartmental knee osteoarthritis.高龄会增加单髁膝关节骨关节炎行胫骨高位截骨术后翻修和围手术期并发症的风险。
Sci Rep. 2021 Dec 21;11(1):24340. doi: 10.1038/s41598-021-03259-y.
9
Risk of revision in UKA versus HTO: a nationwide propensity score-matched study.UKA 与 HTO 翻修风险的比较:一项全国性倾向评分匹配研究。
Arch Orthop Trauma Surg. 2023 Jun;143(6):3457-3469. doi: 10.1007/s00402-022-04658-0. Epub 2022 Oct 20.
10
Predictive factors for satisfaction after contemporary unicompartmental knee arthroplasty and high tibial osteotomy in isolated medial femorotibial osteoarthritis.孤立性内侧股胫关节炎行现代单髁膝关节置换术和胫骨高位截骨术后满意度的预测因素。
Orthop Traumatol Surg Res. 2019 Feb;105(1):77-83. doi: 10.1016/j.otsr.2018.11.001. Epub 2018 Dec 1.

引用本文的文献

1
Spacer-type tibial osteotomy versus open wedge high tibial osteotomy and unicompartmental knee arthroplasty for Kellgren-Lawrence grade 3-4 medial unicompartmental knee osteoarthritis in patients younger than 65 years.对于65岁以下Kellgren-Lawrence 3-4级内侧单髁膝关节骨关节炎患者,间隔型胫骨截骨术与开放性楔形高位胫骨截骨术及单髁膝关节置换术的比较
J Orthop Surg Res. 2025 Jan 27;20(1):99. doi: 10.1186/s13018-025-05533-5.
2
Differential effects of tibia varus deformity on clinical outcomes following high tibial osteotomy and unicompartmental knee arthroplasty for moderate medial compartment osteoarthritis with moderate varus alignment.胫骨内翻畸形对中度内侧间室骨关节炎伴中度内翻畸形行高位胫骨截骨术和单髁膝关节置换术后临床疗效的不同影响。
Arch Orthop Trauma Surg. 2025 Jan 11;145(1):119. doi: 10.1007/s00402-024-05718-3.
3

本文引用的文献

1
Navigated Unicompartmental Knee Arthroplasty: A Different Perspective.导航性单髁膝关节置换术:一种不同的视角。
Clin Orthop Surg. 2021 Dec;13(4):491-498. doi: 10.4055/cios20166. Epub 2021 Apr 29.
2
Intraoperative rotational kinematics and its influence on postoperative clinical outcomes differ according to age in Unicompartmental knee Arthroplasty.在单间室膝关节置换术中,术中旋转运动学及其对术后临床结果的影响因年龄而异。
BMC Musculoskelet Disord. 2021 Jun 1;22(1):505. doi: 10.1186/s12891-021-04371-w.
3
The effect of age on the outcomes of cementless mobile bearing unicompartmental knee replacements.
Opening wedge high tibial osteotomy yields comparable to superior outcomes to unicompartmental knee arthroplasty at 2 years of follow-up in patients suffering from Ahlbäck III knee osteoarthritis: A propensity score-matched analysis.对于患有阿尔贝克III级膝关节骨关节炎的患者,在2年的随访中,开放性楔形高位胫骨截骨术的效果与单髁膝关节置换术相当,甚至更优:一项倾向评分匹配分析。
J Exp Orthop. 2024 Dec 2;11(4):e70105. doi: 10.1002/jeo2.70105. eCollection 2024 Oct.
4
Correlation of revision rate of unicompartmental knee arthroplasty with total knee arthroplasty: a meta-analysis of clinical studies and worldwide arthroplasty registers.单髁膝关节置换术翻修率与全膝关节置换术翻修率的相关性:临床研究和全球关节置换登记处的荟萃分析。
Arch Orthop Trauma Surg. 2024 Nov;144(11):4873-4886. doi: 10.1007/s00402-024-05574-1. Epub 2024 Oct 15.
5
Comparison of Early Complication Rates After High Tibial Osteotomy Versus Unicompartmental Knee Arthroplasty for Knee Osteoarthritis.膝关节骨关节炎的高位胫骨截骨术与单髁膝关节置换术后早期并发症发生率的比较
Orthop J Sports Med. 2024 Jan 4;12(1):23259671231219975. doi: 10.1177/23259671231219975. eCollection 2024 Jan.
6
High tibial osteotomy versus unicompartmental knee arthroplasty for Kellgren-Lawrence grade 3-4 knee osteoarthritis in younger patients: comparable improvements in patient-reported outcomes, adjusted for osteoarthritis grade and sex.胫骨高位截骨术与单髁膝关节置换术治疗年轻患者 Kellgren-Lawrence 分级 3-4 级膝关节骨关节炎:在调整了骨关节炎分级和性别后,患者报告的结局改善相当。
Knee Surg Sports Traumatol Arthrosc. 2023 Nov;31(11):4861-4870. doi: 10.1007/s00167-023-07526-5. Epub 2023 Aug 12.
年龄对非骨水泥固定动平台单髁膝关节置换术结果的影响。
Knee Surg Sports Traumatol Arthrosc. 2022 Mar;30(3):928-938. doi: 10.1007/s00167-020-06428-0. Epub 2021 Feb 12.
4
Unicompartmental knee arthroplasty and revision total knee arthroplasty have a lower risk of venous thromboembolism disease at 30 days than primary total knee arthroplasty.单髁膝关节置换术和全膝关节翻修术在30天时发生静脉血栓栓塞性疾病的风险低于初次全膝关节置换术。
Knee Surg Relat Res. 2020 Nov 4;32(1):59. doi: 10.1186/s43019-020-00078-9.
5
Short-term effectiveness of medial unicompartmental knee arthroplasty in young patients aged less than or equal to 60 years.小于或等于 60 岁的年轻患者行单髁膝关节置换术的短期疗效。
J Orthop Surg (Hong Kong). 2020 Sep-Dec;28(3):2309499020945118. doi: 10.1177/2309499020945118.
6
Therapeutic Effects Comparison and Revision Case Analysis of Unicompartmental Knee Arthroplasty and Open Wedge High Tibial Osteotomy in Treating Medial Knee Osteoarthritis in Patients Under 60 years: A 2-6-year Follow-up Study.60 岁以下内侧膝关节骨关节炎患者行单髁膝关节置换术与开放楔形胫骨高位截骨术的疗效对比及翻修病例分析:2-6 年随访研究。
Orthop Surg. 2020 Dec;12(6):1635-1643. doi: 10.1111/os.12761. Epub 2020 Sep 6.
7
Risk Factors for Unplanned Admission to the Intensive Care Unit After Elective Total Joint Arthroplasty.择期全关节置换术后入住重症监护病房的非计划入院的危险因素。
J Arthroplasty. 2020 Jul;35(7):1937-1940. doi: 10.1016/j.arth.2020.03.003. Epub 2020 Mar 6.
8
Opening wedge high tibial osteotomy allows better outcomes than unicompartmental knee arthroplasty in patients expecting to return to impact sports.对于期望重返撞击性运动的患者,楔形胫骨高位截骨术的效果优于单髁膝关节置换术。
Knee Surg Sports Traumatol Arthrosc. 2020 Dec;28(12):3849-3857. doi: 10.1007/s00167-020-05857-1. Epub 2020 Feb 1.
9
No Differences in Outcomes Scores or Survivorship of Unicompartmental Knee Arthroplasty Between Patients Younger or Older than 55 Years of Age at Minimum 10-Year Followup.在至少 10 年的随访中,在单髁膝关节置换术患者中,年龄在 55 岁以下或以上的患者在结局评分或生存率方面没有差异。
Clin Orthop Relat Res. 2019 Jun;477(6):1434-1446. doi: 10.1097/CORR.0000000000000737.
10
Longer Operative Time Results in a Higher Rate of Subsequent Periprosthetic Joint Infection in Patients Undergoing Primary Joint Arthroplasty.初次关节置换术后,手术时间延长与更高的假体周围关节感染率相关。
J Arthroplasty. 2019 May;34(5):947-953. doi: 10.1016/j.arth.2019.01.027. Epub 2019 Jan 18.