Shetty Vivek, Wagh Yash, Karade Vikas, Maurya Amit, Parihar Mangal, Shekhar Sajeev, Tandel Jignesh
Department of Orthopedics, P. D. Hinduja Hospital and Medical Research Centre, Veer Savarkar Marg, Mahim, Mumbai, Maharashtra 400016 India.
Department of Society of Innovation and Entrepreneurship (SINE), Algosurg Inc., Society of Innovation and Entrepreneurship (SINE), IIT-Bombay, Room no. 501, 5th floor, A3, Raunak Park, Thane West, Mumbai, Maharashtra 400606 India.
Indian J Orthop. 2021 Jul 13;55(5):1150-1157. doi: 10.1007/s43465-021-00456-9. eCollection 2021 Oct.
Patient Specific Instrumentation (PSI) with 3D bone models have been used to improve the outcomes of Total Knee Arthroplasty (TKA). The PSI, however, needs a CT (Computed tomography)/MRI scan to reproduce a bone-based model. However, CT is not a routine imaging method in the TKA and has challenges such as high radiation exposure and increased investigation cost. Any technology or software which could accurately recreate 3D bone models using X-ray would be a cheaper and safer tool. This study is based on one such technology (XrayTo3D) using X-ray to 3D as an alternative to other image-based 3D bone models and PSI available in the market. This study compares the accuracy of XrayTo3D versus a Conventional CT to 3D, in the reconstruction of lower limb bones (femur and tibia).
In an analysis of 45 lower limbs, 11 anatomical parameters were measured [Medial Proximal Tibial Angle-MPTA, Tibial(T)-torsion, T-slope, T-length, Mechanical Lateral Distal Femoral Angle (mLDFA), F-version, F-length, Distal femoral Medio lateral width (F-ML), Distal Femoral Antero Posterior (F-AP), Proximal Tibia Antero Posterior (T-AP), Proximal Tibia Medio Lateral (T-ML) based on landmarks selected by three orthopaedic surgeons(numbers of the authors superscript), on two groups of 3D models, one reconstructed using XrayTo3D and the other using CT. Mean and standard-deviation values were measured for all the parameters in both the groups. Statistical association between both the groups was measured by Pearson's correlation coefficient. Two-sided tests of the mean values were calculated to compare the two measurement methods. The interobserver reproducibility within each group was measured by the intraclass correlation coefficient (ICC). Point-to-surface (P2S) error, in the distal femur and proximal tibia regions of the models reconstructed using XrayTo3D, were also measured.
For all the 11 parameters, no statistically significant difference was found between the 2 groups ( > 0.05). Pearson's correlation coefficients for all the parameters were not significant. The interobserver reproducibility was ranging from 0.90 to 1.00 and 0.90 to 1.00 for the XrayTo3D and CT groups, respectively. The mean P2S distance was 1.0 mm in distal femur and 1.1 mm in proximal tibia which was within the acceptable limits.
The reconstruction accuracy of the XrayTo3D is an accurate, safe and cost effective as compared to a CT-based method.
患者特异性器械(PSI)与三维骨骼模型已被用于改善全膝关节置换术(TKA)的效果。然而,PSI需要进行CT(计算机断层扫描)/MRI扫描以重建基于骨骼的模型。然而,CT并非TKA的常规成像方法,且存在诸如辐射暴露高和检查成本增加等挑战。任何能够使用X射线准确重建三维骨骼模型的技术或软件都将是一种更便宜且更安全的工具。本研究基于一种这样的技术(XrayTo3D),该技术利用X射线生成三维模型,作为市场上其他基于图像的三维骨骼模型和PSI的替代方法。本研究比较了XrayTo3D与传统CT三维重建下肢骨骼(股骨和胫骨)的准确性。
在对45条下肢的分析中,基于三位骨科医生(作者编号上标)选择的标志点,测量了11个解剖参数[胫骨近端内侧角-MPTA、胫骨(T)扭转、T斜率、T长度、股骨远端外侧机械角(mLDFA)、F旋转、F长度、股骨远端内外侧宽度(F-ML)、股骨远端前后径(F-AP)、胫骨近端前后径(T-AP)、胫骨近端内外侧径(T-ML)],在两组三维模型上进行测量,一组使用XrayTo3D重建,另一组使用CT重建。测量两组所有参数的均值和标准差。两组之间的统计关联通过Pearson相关系数进行测量。计算两组均值的双侧检验以比较两种测量方法。每组内观察者间的可重复性通过组内相关系数(ICC)进行测量。还测量了使用XrayTo3D重建的模型在股骨远端和胫骨近端区域的点到面(P2S)误差。
对于所有11个参数,两组之间均未发现统计学上的显著差异(>0.05)。所有参数的Pearson相关系数均不显著。XrayTo3D组和CT组观察者间的可重复性分别为0.90至1.00和0.90至1.00。股骨远端的平均P2S距离为1.0毫米,胫骨近端为1.1毫米,均在可接受范围内。
与基于CT的方法相比,XrayTo3D的重建准确性准确、安全且具有成本效益。